Paralogue Annotation for RYR1 residue 4408

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4408
Reference Amino Acid: A - Alanine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4408

No paralogue variants have been mapped to residue 4408 for RYR1.



RYR1ELLAGMPDPTSDEVHGEQPAGPGGDADGEG>A<SEGAGDAAEGAGDEEEAVHEAGPGGADGAV4438
RYR2ELLANMPDPTQDEVRGDGEEGERKP-LEAA>L<PSEDLTDLKELTEESDLLSD-----IFGLD4383
RYR3KILGDMPDPTQFGIHDDTMEAERAEVMEPG>I<TTELVHFIKGEKGDTDIMSD-----LFGLH4285
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.A4408Pc.13222G>C Putative BenignSIFT: tolerated
Polyphen: