Paralogue Annotation for RYR1 residue 4515

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4515
Reference Amino Acid: P - Proline
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4515

No paralogue variants have been mapped to residue 4515 for RYR1.



RYR1EELPPEPEPEPEPELEPEKADAENGEKEEV>P<EPTPEPPKKQ---------APPSPPPKKEE4536
RYR2--KEEEKEEKEETKSEPEKAEGEDGEKEEK>A<KEDKGKQKLR--------QLHTHRYGEPEV4475
RYR3--AEMKAANEAEGKVESEKADMEDGEKEDK>D<KEEEQAEYLWTEVTKKKKRRCGQKVEKPEA4386
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.P4515Tc.13543C>A Putative BenignSIFT:
Polyphen: