Paralogue Annotation for RYR1 residue 4583

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4583
Reference Amino Acid: V - Valine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4583

No paralogue variants have been mapped to residue 4583 for RYR1.



RYR1LNYLSRNFYTLRFLALFLAFAINFILLFYK>V<SDSPPGEDDMEGSAAGDVSGAGSGGSSGW-4612
RYR2LNYFARNFYNMRMLALFVAFAINFILLFYK>V<STSSVVEGKE------LPTRSSSENAK-VT4545
RYR3LHYLARNFYNLRFLALFVAFAINFILLFYK>V<TEEPLEEETE------DVANLWN-------4450
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.V4583Ic.13747G>A Putative BenignSIFT:
Polyphen: