Paralogue Annotation for RYR1 residue 4590

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4590
Reference Amino Acid: E - Glutamate
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4590

No paralogue variants have been mapped to residue 4590 for RYR1.



RYR1FYTLRFLALFLAFAINFILLFYKVSDSPPG>E<DDMEGSAAGDVSGAGSGGSSGW-GLGAGEE4619
RYR2FYNMRMLALFVAFAINFILLFYKVSTSSVV>E<GKE------LPTRSSSENAK-VTSLDS---4549
RYR3FYNLRFLALFVAFAINFILLFYKVTEEPLE>E<ETE------DVANLWN-------SFND---4454
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.E4590Kc.13768G>A Putative BenignSIFT:
Polyphen: