Paralogue Annotation for RYR1 residue 4636

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4636
Reference Amino Acid: S - Serine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4636

No paralogue variants have been mapped to residue 4636 for RYR1.



RYR1GGSSGW-GLGAGEEAEGDEDENMVYYFLEE>S<TGYMEPALRCLSLLHTLVAFLCIIGYNCLK4666
RYR2ENAK-VTSLDS-----SSHRIIAVHYVLEE>S<SGYMEPTLRILAILHTVISFFCIIGYYCLK4594
RYR3-------SFND-----EEEEEAMVFFVLQE>S<TGYMAPTLRALAIIHTIISLVCVVGYYCLK4499
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.S4636Gc.13906A>G Putative BenignSIFT: tolerated
Polyphen: