Paralogue Annotation for RYR1 residue 491

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 491
Reference Amino Acid: D - Aspartate
Protein Domain:


Paralogue Variants mapped to RYR1 residue 491

No paralogue variants have been mapped to residue 491 for RYR1.



RYR1EEKQSKLRSLRNRQSLFQEEGMLSMVLNCI>D<RLNVYTTAAHFAEFAGEEAAESWKEIVNLL521
RYR2EDKQNRLRALKNRQNLFQEEGMINLVLECI>D<RLHVYSSAAHFADVAGREAGESWKSILNSL533
RYR3EDKQNKLRSLKNRQNLFKEEGMLALVLNCI>D<RLNVYNSVAHFAGIAREESGMAWKEILNLL520
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.D491Ac.1472A>C Putative BenignSIFT:
Polyphen: