Paralogue Annotation for RYR1 residue 4961

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4961
Reference Amino Acid: I - Isoleucine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4961

No paralogue variants have been mapped to residue 4961 for RYR1.



RYR1AIIQGLIIDAFGELRDQQEQVKEDMETKCF>I<CGIGSDYFDTTPHGFETHTLEEHNLANYMF4991
RYR2AIIQGLIIDAFGELRDQQEQVKEDMETKCF>I<CGIGNDYFDTVPHGFETHTLQEHNLANYLF4920
RYR3AIIQGLIIDAFGELRDQQEQVREDMETKCF>I<CGIGNDYFDTTPHGFETHTLQEHNLANYLF4823
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.I4961Mc.14883C>G Putative BenignSIFT: deleterious
Polyphen: