Paralogue Annotation for RYR1 residue 585

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 585
Reference Amino Acid: I - Isoleucine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 585

No paralogue variants have been mapped to residue 585 for RYR1.

RYR1	ASSGILEVLYCVLIESPEVLNIIQENHIKS>I<ISLLDKHGRNHKVLDVLCSLCVCNGVAVRS	615
RYR2	ASSGILEVLHCVLVESPEALNIIKEGHIKS>I<ISLLDKHGRNHKVLDVLCSLCVCHGVAVRS	627
RYR3	SSSGILEVLHCILTESPEALNLIAEGHIKS>I<ISLLDKHGRNHKVLDILCSLCLCNGVAVRA	614
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.I585V	c.1753A>G	Putative Benign		rs200770015	SIFT: Polyphen: probably damaging