Paralogue Annotation for RYR1 residue 656

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 656
Reference Amino Acid: T - Threonine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 656

No paralogue variants have been mapped to residue 656 for RYR1.

RYR1	PGRELLLQTNLINYVTSIRPNIFVGRAEGT>T<QYSKWYFEVMVDEVTPFLTAQATHLRVGWA	686
RYR2	PGRDLLLQTRLVNHVSSMRPNIFLGVSEGS>A<QYKKWYYELMVDHTEPFVTAEATHLRVGWA	698
RYR3	PRRNLLLQTRLINDVTSIRPNIFLGVAEGS>A<QYKKWYFELIIDQVDPFLTAEPTHLRVGWA	685
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.T656M	c.1967C>T	Putative Benign		rs4802472	SIFT: Polyphen: probably damaging