Paralogue Annotation for RYR1 residue 845

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 845
Reference Amino Acid: L - Leucine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 845

No paralogue variants have been mapped to residue 845 for RYR1.

RYR1	LPRERLHLEPIKEYRREGPRGPHLVGPSRC>L<SHTDFVPCPVDTVQIVLPPHLERIREKLAE	875
RYR2	LPKEKLKVEHSREYKQERTYTRDLLGPTVS>L<TQAAFTPIPVDTSQIVLPPHLERIREKLAE	887
RYR3	LPKEKMRLEPVKEYKRDADGIRDLLGTTQF>L<SQASFIPCPVDTSQVILPPHLEKIRDRLAE	874
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.L845F	c.2533C>T	Putative Benign		rs201545585	SIFT: Polyphen: probably damaging