Paralogue Annotation for RYR1 residue 849

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 849
Reference Amino Acid: D - Aspartate
Protein Domain:

Paralogue Variants mapped to RYR1 residue 849

No paralogue variants have been mapped to residue 849 for RYR1.

RYR1	RLHLEPIKEYRREGPRGPHLVGPSRCLSHT>D<FVPCPVDTVQIVLPPHLERIREKLAENIHE	879
RYR2	KLKVEHSREYKQERTYTRDLLGPTVSLTQA>A<FTPIPVDTSQIVLPPHLERIREKLAENIHE	891
RYR3	KMRLEPVKEYKRDADGIRDLLGTTQFLSQA>S<FIPCPVDTSQVILPPHLEKIRDRLAENIHE	878
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.D849N	c.2545G>A	Putative Benign		rs200893443	SIFT: Polyphen: probably damaging