Paralogue Annotation for RYR1 residue 871

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 871
Reference Amino Acid: E - Glutamate
Protein Domain:

Paralogue Variants mapped to RYR1 residue 871

No paralogue variants have been mapped to residue 871 for RYR1.

RYR1	PSRCLSHTDFVPCPVDTVQIVLPPHLERIR>E<KLAENIHELWALTRIEQGWTYGPVRDDNKR	901
RYR2	PTVSLTQAAFTPIPVDTSQIVLPPHLERIR>E<KLAENIHELWVMNKIELGWQYGPVRDDNKR	913
RYR3	TTQFLSQASFIPCPVDTSQVILPPHLEKIR>D<RLAENIHELWGMNKIELGWTFGKIRDDNKR	900
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.E871K	c.2611G>A	Putative Benign		rs267605463	SIFT: deleterious Polyphen: probably damaging