Paralogue Annotation for RYR1 residue 966

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 966
Reference Amino Acid: P - Proline
Protein Domain:

Paralogue Variants mapped to RYR1 residue 966

No paralogue variants have been mapped to residue 966 for RYR1.

RYR1	CHVGMADEKAEDNLKKTKLPKTYMMSNGYK>P<APLDLSHVRLTPAQTTLVDRLAENGHNVWA	996
RYR2	CHVGISDEHAEDKVKKMKLPKNYQLTSGYK>P<APMDLSFIKLTPSQEAMVDKLAENAHNVWA	1008
RYR3	CHIAHVNPAAEEDLKKVKLPKNYMMSNGYK>P<APLDLSDVKLLPPQEILVDKLAENAHNVWA	995
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.P966L	c.2897C>T	Putative Benign		rs143179371	SIFT: Polyphen: probably damaging