Paralogue Annotation for RYR2 residue 1858

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1858
Reference Amino Acid: E - Glutamate
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 1858

No paralogue variants have been mapped to residue 1858 for RYR2.



RYR2LLIMGIFHNEDLKHILQLIEPSVFKEAATP>E<EESDTL--E-K---ELS----VDDAK-LQG1877
RYR1LLVMGIFGDEDVKQILKMIEPEVFTEEEEE>E<DEEEEGEEEDEEEKEEDEEETAQEKEDEEK1908
RYR3LLVMGVFDDDDVRQILLLIDPSVFGEHSAG>T<EEGAEK--E-E---VTQ----VEEKA-VEA1781
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.E1858Vc.5573A>T Putative BenignSIFT:
Polyphen:
p.E1858Gc.5573A>G Putative BenignSIFT:
Polyphen: