Paralogue Annotation for RYR2 residue 1865

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1865
Reference Amino Acid: E - Glutamate
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 1865

No paralogue variants have been mapped to residue 1865 for RYR2.



RYR2EDLKHILQLIEPSVFKEAATPEEESDTL-->E<-K---ELS----VDDAK-LQGAGEE--EAK1884
RYR1EDVKQILKMIEPEVFTEEEEEEDEEEEGEE>E<DEEEKEEDEEETAQEKEDEEKEEEEAAEGE1917
RYR3DDVRQILLLIDPSVFGEHSAGTEEGAEK-->E<-E---VTQ----VEEKA-VEAG-----EKA1785
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.E1865Kc.5593G>A Putative BenignSIFT: tolerated
Polyphen: benign