Paralogue Annotation for RYR2 residue 1921

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1921
Reference Amino Acid: R - Arginine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 1921

No paralogue variants have been mapped to residue 1921 for RYR2.



RYR2EGLLQMKLPEPVKLQMCLLLQYLCDCQVRH>R<IEAIVAFSDDFVAKLQDNQRFRYNEVMQAL1951
RYR1EGLLQMKLPESVKLQMCHLLEYFCDQELQH>R<VESLAAFAERYVDKLQANQRSRYGLLIKAF1984
RYR3KGLLQTRLPESVKLQMCELLSYLCDCELQH>R<VEAIVAFGDIYVSKLQANQKFRYNELMQAL1852
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R1921Qc.5762G>A Putative BenignSIFT: deleterious
Polyphen: probably damaging
p.R1921Wc.5761C>T Putative BenignSIFT:
Polyphen: