Paralogue Annotation for RYR2 residue 3589

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 3589
Reference Amino Acid: K - Lysine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 3589

No paralogue variants have been mapped to residue 3589 for RYR2.



RYR2HLEQKSKRVGRRHYCL-VEHPQRSKKAVWH>K<LLSKQRKRAVVACFRMAPLYNLPRHRAVNL3619
RYR1-----QEVSAVLYYLDQTEHPYKSKKAVWH>K<LLSKQRRRAVVACFRMTPLYNLPTHRACNM3652
RYR3-----QRISAAVFHLEQVEQPLRSKKAVWH>K<LLSKQRKRAVVACFRMAPLYNLPRHRSINL3507
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Lys3589Thrc.10766A>C UnknownSIFT:
Polyphen: