Paralogue Annotation for RYR2 residue 4301

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4301
Reference Amino Acid: V - Valine
Protein Domain: Transmembrane region


Paralogue Variants mapped to RYR2 residue 4301

No paralogue variants have been mapped to residue 4301 for RYR2.



RYR2VKKMTVKDMVTAFFSSYWSIFMTLLHFVAS>V<FRGFFRIICSLLLGGSLVEGAKKIKVAELL4331
RYR1LRRLTAREAATAVAALLWAAVTRAGAAGAG>A<AAGALGLLWGSLFGGGLVEGAKKVTVTELL4380
RYR3VKKMTAKELVKVLFSFFWMLFVGLFQLLFT>I<LGGIFQILWSTVFGGGLVEGAKNIRVTKIL4232
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.V4301Lc.12901G>C Putative BenignSIFT:
Polyphen: