Paralogue Annotation for RYR2 residue 4345

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4345
Reference Amino Acid: D - Aspartate
Protein Domain: Transmembrane region


Paralogue Variants mapped to RYR2 residue 4345

No paralogue variants have been mapped to residue 4345 for RYR2.



RYR2GGSLVEGAKKIKVAELLANMPDPTQDEVRG>D<GEEGERKP-LEAALPSEDLTDLKELTEESD4374
RYR1GGGLVEGAKKVTVTELLAGMPDPTSDEVHG>E<QPAGPGGDADGEGASEGAGDAAEGAGDEEE4424
RYR3GGGLVEGAKNIRVTKILGDMPDPTQFGIHD>D<TMEAERAEVMEPGITTELVHFIKGEKGDTD4276
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.D4345Ec.13035T>A Putative BenignSIFT:
Polyphen: