Paralogue Annotation for RYR2 residue 4447

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4447
Reference Amino Acid: G - Glycine
Protein Domain: Transmembrane region


Paralogue Variants mapped to RYR2 residue 4447

No paralogue variants have been mapped to residue 4447 for RYR2.



RYR2Q--KA---KEEEKEEKEETKSEPEKAEGED>G<EKEEKAKEDKGKQKLR--------QLHTHR4469
RYR1GVDGVEEELPPEPEPEPEPELEPEKADAEN>G<EKEEVPEPTPEPPKKQ---------APPSP4530
RYR3---QA---AEMKAANEAEGKVESEKADMED>G<EKEDKDKEEEQAEYLWTEVTKKKKRRCGQK4380
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.G4447Ec.13340G>A Putative BenignSIFT:
Polyphen: