Paralogue Annotation for RYR2 residue 4460

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4460
Reference Amino Acid: Q - Glutamine
Protein Domain: Transmembrane region


Paralogue Variants mapped to RYR2 residue 4460

No paralogue variants have been mapped to residue 4460 for RYR2.



RYR2EEKEETKSEPEKAEGEDGEKEEKAKEDKGK>Q<KLR--------QLHTHRYGEPEVPESAFWK4482
RYR1EPEPEPELEPEKADAENGEKEEVPEPTPEP>P<KKQ---------APPSPPPKKEEAGGEFWG4543
RYR3ANEAEGKVESEKADMEDGEKEDKDKEEEQA>E<YLWTEVTKKKKRRCGQKVEKPEAFTANFFK4393
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Q4460Rc.13379A>G Putative BenignSIFT:
Polyphen: