Paralogue Annotation for RYR2 residue 539

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 539
Reference Amino Acid: A - Alanine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 539

No paralogue variants have been mapped to residue 539 for RYR2.



RYR2SSAAHFADVAGREAGESWKSILNSLYELLA>A<LIRGNRKNCAQFSGSLDWLISRLERLEASS569
RYR1TTAAHFAEFAGEEAAESWKEIVNLLYELLA>S<LIRGNRSNCALFSTNLDWLVSKLDRLEASS557
RYR3NSVAHFAGIAREESGMAWKEILNLLYKLLA>A<LIRGNRNNCAQFSNNLDWLISKLDRLESSS556
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.A539Vc.1616C>T Putative BenignSIFT:
Polyphen: