Paralogue Annotation for RYR2 residue 786

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 786
Reference Amino Acid: G - Glycine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 786

No paralogue variants have been mapped to residue 786 for RYR2.



RYR2SCCLDLSAPSISFRINGQPVQGMFENFNID>G<LFFPVVSFSAGIKVRFLLGGRHGEFKFLPP816
RYR1SCCLDLSVPSISFRINGCPVQGVFESFNLD>G<LFFPVVSFSAGVKVRFLLGGRHGEFKFLPP804
RYR3SCCLDLGVPSISFRINGQPVQGMFENFNTD>G<LFFPVMSFSAGVKVRFLMGGRHGEFKFLPP803
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.G786Dc.2357G>A Putative BenignSIFT: deleterious
Polyphen: probably damaging