Paralogue Annotation for RYR2 residue 836

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 836
Reference Amino Acid: H - Histidine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 836

No paralogue variants have been mapped to residue 836 for RYR2.

RYR2	GRHGEFKFLPPPGYAPCYEAVLPKEKLKVE>H<SREYKQERTYTRDLLGPTVSLTQAAFTPIP	866
RYR1	GRHGEFKFLPPPGYAPCHEAVLPRERLHLE>P<IKEYRREGPRGPHLVGPSRCLSHTDFVPCP	854
RYR3	GRHGEFKFLPPSGYAPCYEALLPKEKMRLE>P<VKEYKRDADGIRDLLGTTQFLSQASFIPCP	853
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.H836P	c.2507A>C	Putative Benign		rs76474894	SIFT: tolerated Polyphen: benign
p.H836N	c.2506C>A	Putative Benign			SIFT: Polyphen:
p.His836Arg	c.2507A>G	Unknown			SIFT: Polyphen: