No paralogue variants have been mapped to residue 149 for SCN5A.
| SCN5A | PIRRAAVKILVHSLFNMLIMCTILTNCVFM>A<QH------D-PPPWT--KYVEYTFTA-IYT | 169 |
| SCN1A | PLRKIAIKILVHSLFSMLIMCTILTNCVFM>T<MS------N-PPDWT--KNVEYTFTG-IYT | 166 |
| SCN2A | PIRKLAIKILVHSLFNMLIMCTILTNCVFM>T<MS------N-PPDWT--KNVEYTFTG-IYT | 167 |
| SCN3A | PVRKIAIKILVHSLFSMLIMCTILTNCVFM>T<LS------N-PPDWT--KNVEYTFTG-IYT | 166 |
| SCN4A | VVRRGAIKVLIHALFSMFIMITILTNCVFM>T<MS------D-PPPWS--KNVEYTFTG-IYT | 169 |
| SCN7A | CIRRTTIKVLVHPFFQLFILISVLIDCVFM>S<LT------N-LPKWR--PVLENTLLG-IYT | 156 |
| SCN8A | LIRRIAIKILIHSVFSMIIMCTILTNCVFM>T<FS------N-PPDWS--KNVEYTFTG-IYT | 170 |
| SCN9A | PLRRISIKILVHSLFSMLIMCTILTNCIFM>T<MN------N-PPDWT--KNVEYTFTG-IYT | 164 |
| SCN10A | LIRRTAIKVSVHSWFSLFITVTILVNCVCM>T<RT------D-LPE-----KIEYVFTV-IYT | 165 |
| SCN11A | SIRSLAIRVSVHSLFSMFIIGTVIINCVFM>A<TGPA-K--NSNSNNT--DIAECVFTG-IYI | 171 |
| CACNA1A | VVRKYAKKITEWPPFEYMILATIIANCIVL>A<LEQHLPDDDKTPMSERLDDTEPYFIG-IFC | 145 |
| CACNA1B | VVRKYAKRITEWPPFEYMILATIIANCIVL>A<LEQHLPDGDKTPMSERLDDTEPYFIG-IFC | 142 |
| CACNA1C | PIRRACISIVEWKPFEIIILLTIFANCVAL>A<IYIPFPEDDSNATNSNLERVEYLFLI-IFT | 171 |
| CACNA1D | PIRRACISIVEWKPFDIFILLAIFANCVAL>A<IYIPFPEDDSNSTNHNLEKVEYAFLI-IFT | 173 |
| CACNA1E | IVRKYAKKLIDWPPFEYMILATIIANCIVL>A<LEQHLPEDDKTPMSRRLEKTEPYFIG-IFC | 136 |
| CACNA1F | PLRRSCISIVEWKPFDILILLTIFANCVAL>G<VYIPFPEDDSNTANHNLEQVEYVFLV-IFT | 139 |
| CACNA1G | RPRSWCLRTVCNPWFERISMLVILLNCVTL>G<MFRPCEDIACDSQRCRILQAFDDFIFAFFA | 129 |
| CACNA1H | RPRSWCLRLVCNPWFEHVSMLVIMLNCVTL>G<MFRPCEDVECGSERCNILEAFDAFIFAFFA | 148 |
| CACNA1I | SPRNWCIKMVCNPWFECVSMLVILLNCVTL>G<MYQPCDDMDCLSDRCKILQVFDDFIFIFFA | 127 |
| CACNA1S | PLRKACISIVEWKPFETIILLTIFANCVAL>A<VYLPMPEDDNNSLNLGLEKLEYFFLI-VFS | 98 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.A149V | c.446C>T | Other Cardiac Phenotype | SIFT: Polyphen: | ||
| Reports | Other Cardiac Phenotype | Cardiac channelopathy testing in 274 ethnically diverse sudden unexplained deaths. Forensic Sci Int. 2014 237:90-9. doi: 10.1016/j.forsciint.2014.01.014. 24631775 | |||