Paralogue Annotation for SCN5A residue 1981

Residue details

Gene: SCN5A
Reference Sequences: LRG: LRG_289, Ensembl variant: ENST00000333535 / ENSP00000328968
Amino Acid Position: 1981
Reference Amino Acid: T - Threonine
Protein Domain: C-terminus


Paralogue Variants mapped to SCN5A residue 1981

No paralogue variants have been mapped to residue 1981 for SCN5A.



SCN5A----SSISSTSF-P----------PSYDSV>T<------------------------------1981
SCN1A----DLTMSTAACP----------PSYDRV>T<------------------------------1990
SCN2A----DMTPSTTS-P----------PSYDSV>T<------------------------------1979
SCN3A----DGSSSTTS-P----------PSYDSV>T<------------------------------1974
SCN4A----EKGEAGDA-G----------PTMGLM>P<------------------------------1809
SCN7A------------------------------>-<------------------------------
SCN8A----ESTPSTAS-L----------PSYDSV>T<------------------------------1951
SCN9A----DATSSTTS-P----------PSYDSV>T<------------------------------1951
SCN10A----ETASATSF-P----------PSYESV>T<------------------------------1925
SCN11A----L--------------------CNGDL>S<------------------------------1779
CACNA1A------------------------------>-<--------ENQRRRGRPR----------GN2111
CACNA1B------------------------------>-<--------ETQ-----P-------------2012
CACNA1CPSHEKLVDSTFTPSSY-------SSTGSNA>N<I--NNANNTALGRLPRPAG----YPSTVST1790
CACNA1DPLFPPAGNSVCHNHHNHNSIGKQVPTSTNA>N<L--NNANMSKAAHGKRPSIGNLEHVSENGH1805
CACNA1E------------------------------>-<--------DPQ-------------------2009
CACNA1F--SDDDRG---------------TPTSSQP>S<V--PQAGSNTHRRGSG--------------1723
CACNA1GPKDAPHLLQPHS-APT--------WGTIPK>L<PPPG---RSPL------------------A2126
CACNA1HPADEEVSHITSS-ACP--------WQPTAE>P<H-----------------------------2118
CACNA1IATGSDTSLDASP-SSS--------AGSL-Q>T<TLED---SLT--------------------2037
CACNA1SPVFLE---D-FPQDPR-------TNPLARA>N<T--NNAN-----------------------1665
cons                              > <                              

See full Alignment of Paralogues


Known Variants in SCN5A

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T1981Sc.5942C>G Putative Benignrs76759236SIFT: deleterious
Polyphen: probably damaging