Paralogue Annotation for SCN5A residue 92

Residue details

Gene: SCN5A
Reference Sequences: LRG: LRG_289, Ensembl variant: ENST00000333535 / ENSP00000328968
Amino Acid Position: 92
Reference Amino Acid: T - Threonine
Protein Domain: N-terminus

Paralogue Variants mapped to SCN5A residue 92

No paralogue variants have been mapped to residue 92 for SCN5A.

SCN5A	KLPDLYGNPPQELIGEPLEDLDPFYSTQK->T<FI-VLNKGKTIFRFSATNALYVLSPFHPIR	121
SCN1A	NLPFIYGDIPPEMVSEPLEDLDPYYINKK->T<FI-VLNKGKAIFRFSATSALYILTPFNPLR	118
SCN2A	SLPFIYGDIPPEMVSVPLEDLDPYYINKK->T<FI-VLNKGKAISRFSATPALYILTPFNPIR	119
SCN3A	NLPFIYGDIPPEMVSEPLEDLDPYYINKK->T<FI-VMNKGKAIFRFSATSALYILTPLNPVR	118
SCN4A	NLPMIYGDPPPEVIGIPLEDLDPYYSNKK->T<FI-VLNKGKAIFRFSATPALYLLSPFSVVR	121
SCN7A	KLPFIYGNLSQGMVSEPLEDVDPYYYKKKN>T<FI-VLNKNRTIFRFNAASILCTLSPFNCIR	108
SCN8A	SLPFIYGDIPQGLVAVPLEDFDPYYLTQK->T<FV-VLNRGKTLFRFSATPALYILSPFNLIR	122
SCN9A	QLPFIYGDIPPGMVSEPLEDLDPYYADKK->T<FI-VLNKGKTIFRFNATPALYMLSPFSPLR	116
SCN10A	QLPKFYGELPAELIGEPLEDLDPFYSTHR->T<FM-VLNKGRTISRFSATRALWLFSPFNLIR	120
SCN11A	KLPKLYGDIPRELIGKPLEDLDPFYRNHK->T<FM-VLNRKRTIYRFSAKHALFIFGPFNSIR	119
CACNA1A	--PGA-----------QRMYKQSMAQRART>M<AL-YNPIPVRQNCLTVNRSLFLFSEDNVVR	88
CACNA1B	--PGQ-----------RVLYKQSIAQRART>M<AL-YNPIPVKQNCFTVNRSLFVFSEDNVVR	85
CACNA1C	IDAARQAKLMGSAGNATISTVSST-QRKRQ>Q<YG-KPKKQGSTTATRPPRALLCLTLKNPIR	114
CACNA1D	IDAARQAKAAQTMSTSAPPPVGSLSQRKRQ>Q<YA-KSKKQGNSSNSRPARALFCLSLNNPIR	116
CACNA1E	--SGQ-----------AAAYKQTKAQRART>M<AL-YNPIPVRQNCFTVNRSLFIFGEDNIVR	79
CACNA1F	---AV--------EGESSGASGLGTPKRRN>Q<HS-KHKTVAVASAQRSPRALFCLTLANPLR	82
CACNA1G	---G-----------PGSA-------EKDP>G<-SADSEAEGLPYPALAPVVFFYLSQDSRPR	71
CACNA1H	---S-----------P-AA-------ERGA>E<LG-ADEEQRVPYPALAATVFFCLGQTTRPR	90
CACNA1I	--PS-----------SPPG-------LEEP>L<-D-G-ADPHVPHPDLAPIAFFCLRQTTSPR	69
CACNA1S	----------------------SSPQDEGL>R<KK-QPKKPVPEILPRPPRALFCLTLENPLR	41
cons	> <

See full Alignment of Paralogues

Known Variants in SCN5A

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.T92I	c.275C>T	Putative Benign			SIFT: Polyphen: