The table below lists the 0 rare (MAF<0.0001 in ExAC) protein-altering TNNC1 variants identified in a cohort of 632 HCM patients. As the background population rate of rare protein-altering TNNC1 variants (0.00060) is greater than this case frequency (0.00000), there is no excess of variants in this HCM patient cohort, suggesting that protein-altering TNNC1 variants are not causative for HCM.
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