TRIM55 missense variants in ExAC

TRIM55 gene summary
TRIM55 variants in

The table below lists the TRIM55 missense variants found in the ExAC population database. Click on each variant for more details, including presence in the 1000 Genomes and Exome Sequencing Project databases, a breakdown by ethnic class and the variant's role in inherited cardiac disease. Use the form below to customise the variant selection. The table can be sorted by variant location, variant type or ExAC frequency.




No. Genomic coord.✝ Variant (CDS)▼ Variant (Protein) Variant Type▼ ExAC frequency▼Populations*
1. 67064654 c.1028A>G p.K343R missense 0.14103252●●●●●●
2. 67066396 c.1351C>T p.R451W missense 0.00191994●●●●●●
3. 67047301 c.418G>A p.E140K missense 0.00180381●●●●●●
4. 67047241 c.358G>T p.D120Y missense 0.00065108●●●●●●
5. 67066435 c.1390G>A p.E464K missense 0.00050261●●●●●●
6. 67066394 c.1349C>T p.T450I missense 0.00046968●●●●●●
7. 67061980 c.704G>A p.R235Q missense 0.00040366●●●●●●
8. 67086762 c.1581T>G p.S527R missense 0.00026585●●●●●●
9. 67066511 c.1466C>T p.A489V missense 0.00026424●●●●●●
10. 67061983 c.707C>T p.T236I missense 0.00025538●●●●●●
11. 67047352 c.469C>A p.Q157K missense 0.00024710●●●●●●
12. 67066367 c.1322T>G p.F441C missense 0.00019783●●●●●●
13. 67064719 c.1093G>A p.E365K missense 0.00019018●●●●●●
14. 67040600 c.230G>A p.R77H missense 0.00016485●●●●●●
15. 67040549 c.179C>T p.P60L missense 0.00014272●●●●●●
16. 67062681 c.965G>A p.R322H missense 0.00014008●●●●●●
17. 67047274 c.391C>T p.R131C missense 0.00014003●●●●●●
18. 67064800 c.1174C>A p.P392T missense 0.00013234●●●●●●
19. 67066544 c.1499C>T p.T500I missense 0.00011568●●●●●●
20. 67062012 c.736G>T p.A246S missense 0.00010709●●●●●●
21. 67061923 c.647A>G p.D216G missense 0.00009915●●●●●●
22. 67064788 c.1162C>G p.P388A missense 0.00007439●●●●●●
23. 67086718 c.1537G>T p.A513S missense 0.00007415●●●●●●
24. 67062015 c.739C>G p.L247V missense 0.00007414●●●●●●
25. 67047354 c.471G>C p.Q157H missense 0.00007413●●●●●●
26. 67064632 c.1006G>C p.E336Q missense 0.00006922●●●●●●
27. 67064686 c.1060G>A p.V354I missense 0.00005927●●●●●●
28. 67066516 c.1471G>A p.E491K missense 0.00005778●●●●●●
29. 67086721 c.1540C>T p.P514S missense 0.00005767●●●●●●
30. 67062624 c.908G>C p.G303A missense 0.00005767●●●●●●
31. 67040626 c.256G>A p.V86I missense 0.00005767●●●●●●
32. 67047376 c.493T>C p.F165L missense 0.00005766●●●●●●
33. 67064641 c.1015G>A p.G339R missense 0.00005607●●●●●●
34. 67062082 c.806T>G p.M269R missense 0.00004945●●●●●●
35. 67086731 c.1550A>G p.Q517R missense 0.00004944●●●●●●
36. 67062635 c.919A>G p.M307V missense 0.00004943●●●●●●
37. 67062692 c.976T>G p.F326V missense 0.00004121●●●●●●
38. 67062593 c.877A>G p.K293E missense 0.00004120●●●●●●
39. 67086719 c.1538C>T p.A513V missense 0.00004120●●●●●●
40. 67064644 c.1018G>A p.E340K missense 0.00003837●●●●●●
41. 67066355 c.1310C>T p.A437V missense 0.00003298●●●●●●
42. 67086793 c.1612T>G p.F538V missense 0.00003298●●●●●●
43. 67062637 c.921G>A p.M307I missense 0.00003296●●●●●●
44. 67062624 c.908G>A p.G303D missense 0.00003295●●●●●●
45. 67047290 c.407G>C p.C136S missense 0.00003295●●●●●●
46. 67039576 c.73A>G p.I25V missense 0.00003295●●●●●●
47. 67064678 c.1052G>T p.G351V missense 0.00002611●●●●●●
48. 67064825 c.1199C>T p.P400L missense 0.00002486●●●●●●
49. 67064752 c.1126G>T p.A376S missense 0.00002479●●●●●●
50. 67049376 c.554G>A p.R185Q missense 0.00002479●●●●●●
51. 67066518 c.1473G>T p.E491D missense 0.00002476●●●●●●
52. 67062582 c.866C>T p.S289L missense 0.00002474●●●●●●
53. 67062087 c.811G>A p.E271K missense 0.00002473●●●●●●
54. 67086752 c.1571C>T p.A524V missense 0.00002472●●●●●●
55. 67086717 c.1536G>C p.E512D missense 0.00002472●●●●●●
56. 67062636 c.920T>G p.M307R missense 0.00002472●●●●●●
57. 67066401 c.1356A>T p.K452N missense 0.00002472●●●●●●
58. 67062596 c.880G>A p.A294T missense 0.00002472●●●●●●
59. 67047371 c.488A>G p.H163R missense 0.00002471●●●●●●
60. 67062009 c.733C>T p.R245C missense 0.00002471●●●●●●
61. 67039604 c.101C>T p.T34M missense 0.00002471●●●●●●
62. 67064666 c.1040G>A p.G347E missense 0.00001861●●●●●●
63. 67064851 c.1225C>T p.P409S missense 0.00001668●●●●●●
64. 67061906 c.630G>C p.E210D missense 0.00001660●●●●●●
65. 67066561 c.1516A>G p.T506A missense 0.00001660●●●●●●
66. 67049346 c.524G>C p.G175A missense 0.00001657●●●●●●
67. 67066306 c.1261G>A p.E421K missense 0.00001654●●●●●●
68. 67064798 c.1172T>A p.L391H missense 0.00001654●●●●●●
69. 67066307 c.1262A>G p.E421G missense 0.00001654●●●●●●
70. 67049360 c.538G>A p.V180M missense 0.00001653●●●●●●
71. 67040582 c.212C>G p.A71G missense 0.00001652●●●●●●
72. 67066507 c.1462G>A p.A488T missense 0.00001652●●●●●●
73. 67049363 c.541G>T p.G181C missense 0.00001652●●●●●●
74. 67049371 c.549C>A p.N183K missense 0.00001652●●●●●●
75. 67066508 c.1463C>T p.A488V missense 0.00001651●●●●●●
76. 67066331 c.1286C>T p.P429L missense 0.00001651●●●●●●
77. 67061950 c.674G>A p.R225K missense 0.00001649●●●●●●
78. 67040594 c.224G>A p.R75Q missense 0.00001649●●●●●●
79. 67086790 c.1609A>G p.I537V missense 0.00001649●●●●●●
80. 67066471 c.1426G>A p.D476N missense 0.00001648●●●●●●
81. 67086739 c.1558G>T p.A520S missense 0.00001648●●●●●●
82. 67062603 c.887A>T p.Q296L missense 0.00001648●●●●●●
83. 67047251 c.368T>C p.M123T missense 0.00001648●●●●●●
84. 67040608 c.238T>C p.S80P missense 0.00001648●●●●●●
85. 67086749 c.1568C>T p.P523L missense 0.00001648●●●●●●
86. 67062689 c.973G>A p.D325N missense 0.00001648●●●●●●
87. 67047343 c.460A>G p.K154E missense 0.00001647●●●●●●
88. 67062006 c.730G>A p.V244I missense 0.00001647●●●●●●
89. 67064639 c.1013G>A p.G338D missense 0.00001506●●●●●●
90. 67061880 c.604G>C p.E202Q missense 0.00000853●●●●●●
91. 67066495 c.1450G>C p.V484L missense 0.00000852●●●●●●
92. 67040539 c.169G>A p.A57T missense 0.00000851●●●●●●
93. 67049417 c.595A>T p.T199S missense 0.00000839●●●●●●
94. 67049411 c.589T>A p.C197S missense 0.00000835●●●●●●
95. 67066282 c.1237G>A p.G413R missense 0.00000834●●●●●●
96. 67061899 c.623A>G p.K208R missense 0.00000833●●●●●●
97. 67040557 c.187C>A p.P63T missense 0.00000833●●●●●●
98. 67049334 c.512A>G p.E171G missense 0.00000833●●●●●●
99. 67061901 c.625C>A p.Q209K missense 0.00000832●●●●●●
100. 67064843 c.1217C>T p.A406V missense 0.00000832●●●●●●
101. 67049402 c.580G>A p.E194K missense 0.00000831●●●●●●
102. 67040561 c.191C>T p.T64I missense 0.00000831●●●●●●
103. 67064840 c.1214C>T p.A405V missense 0.00000831●●●●●●
104. 67066561 c.1516A>T p.T506S missense 0.00000830●●●●●●
105. 67064831 c.1205T>A p.L402Q missense 0.00000830●●●●●●
106. 67064836 c.1210C>T p.P404S missense 0.00000830●●●●●●
107. 67049400 c.578T>A p.L193Q missense 0.00000830●●●●●●
108. 67040563 c.193A>G p.R65G missense 0.00000830●●●●●●
109. 67062462 c.848C>G p.T283S missense 0.00000830●●●●●●
110. 67064822 c.1196C>T p.P399L missense 0.00000829●●●●●●
111. 67062474 c.860A>T p.K287I missense 0.00000829●●●●●●
112. 67061910 c.634T>C p.C212R missense 0.00000829●●●●●●
113. 67049351 c.529G>A p.A177T missense 0.00000828●●●●●●
114. 67064710 c.1084G>A p.V362I missense 0.00000828●●●●●●
115. 67064809 c.1183T>C p.S395P missense 0.00000828●●●●●●
116. 67064810 c.1184C>T p.S395F missense 0.00000828●●●●●●
117. 67066300 c.1255G>C p.G419R missense 0.00000828●●●●●●
118. 67064819 c.1193C>A p.P398Q missense 0.00000828●●●●●●
119. 67049355 c.533T>C p.I178T missense 0.00000827●●●●●●
120. 67040575 c.205A>G p.T69A missense 0.00000827●●●●●●
121. 67066548 c.1503T>G p.S501R missense 0.00000827●●●●●●
122. 67064722 c.1096T>C p.F366L missense 0.00000827●●●●●●
123. 67064801 c.1175C>T p.P392L missense 0.00000827●●●●●●
124. 67049354 c.532A>G p.I178V missense 0.00000827●●●●●●
125. 67064743 c.1117C>A p.P373T missense 0.00000826●●●●●●
126. 67066535 c.1490G>A p.G497D missense 0.00000826●●●●●●
127. 67064764 c.1138T>C p.S380P missense 0.00000826●●●●●●
128. 67066523 c.1478C>A p.A493E missense 0.00000826●●●●●●
129. 67061929 c.653T>C p.L218P missense 0.00000826●●●●●●
130. 67066507 c.1462G>T p.A488S missense 0.00000826●●●●●●
131. 67064782 c.1156G>C p.A386P missense 0.00000826●●●●●●
132. 67066327 c.1282A>G p.T428A missense 0.00000826●●●●●●
133. 67066534 c.1489G>T p.G497C missense 0.00000826●●●●●●
134. 67064735 c.1109A>G p.D370G missense 0.00000826●●●●●●
135. 67066511 c.1466C>G p.A489G missense 0.00000826●●●●●●
136. 67039670 c.167A>G p.Q56R missense 0.00000825●●●●●●
137. 67066337 c.1292C>T p.P431L missense 0.00000825●●●●●●
138. 67062577 c.861A>C p.K287N missense 0.00000825●●●●●●
139. 67086811 c.1630A>C p.N544H missense 0.00000825●●●●●●
140. 67061932 c.656A>G p.Y219C missense 0.00000825●●●●●●
141. 67062578 c.862A>G p.I288V missense 0.00000825●●●●●●
142. 67062643 c.927C>A p.H309Q missense 0.00000824●●●●●●
143. 67047296 c.413A>G p.N138S missense 0.00000824●●●●●●
144. 67086734 c.1553G>A p.G518E missense 0.00000824●●●●●●
145. 67040638 c.268C>A p.H90N missense 0.00000824●●●●●●
146. 67061943 c.667G>A p.E223K missense 0.00000824●●●●●●
147. 67062597 c.881C>T p.A294V missense 0.00000824●●●●●●
148. 67061988 c.712G>C p.E238Q missense 0.00000824●●●●●●
149. 67062070 c.794G>A p.G265E missense 0.00000824●●●●●●
150. 67062692 c.976T>C p.F326L missense 0.00000824●●●●●●
151. 67062010 c.734G>A p.R245H missense 0.00000824●●●●●●
152. 67039573 c.70C>T p.L24F missense 0.00000824●●●●●●
153. 67086785 c.1604G>A p.R535H missense 0.00000824●●●●●●
154. 67040707 c.337A>G p.T113A missense 0.00000824●●●●●●
155. 67062003 c.727C>T p.H243Y missense 0.00000824●●●●●●
156. 67047256 c.373G>A p.E125K missense 0.00000824●●●●●●
157. 67066417 c.1372C>A p.P458T missense 0.00000824●●●●●●
158. 67066427 c.1382C>T p.P461L missense 0.00000824●●●●●●
159. 67062033 c.757G>A p.D253N missense 0.00000824●●●●●●
160. 67062680 c.964C>T p.R322C missense 0.00000824●●●●●●
161. 67066376 c.1331G>A p.S444N missense 0.00000824●●●●●●
162. 67039609 c.106C>T p.P36S missense 0.00000824●●●●●●
163. 67040605 c.235C>G p.P79A missense 0.00000824●●●●●●
164. 67062678 c.962T>C p.I321T missense 0.00000824●●●●●●
165. 67086757 c.1576G>A p.G526S missense 0.00000824●●●●●●
166. 67047331 c.448T>A p.F150I missense 0.00000824●●●●●●
167. 67040658 c.288G>T p.Q96H missense 0.00000824●●●●●●
168. 67066484 c.1439G>A p.R480Q missense 0.00000824●●●●●●
169. 67066475 c.1430C>T p.S477L missense 0.00000824●●●●●●
170. 67039576 c.73A>C p.I25L missense 0.00000824●●●●●●
171. 67086734 c.1553G>C p.G518A missense 0.00000824●●●●●●
172. 67039655 c.152C>T p.A51V missense 0.00000824●●●●●●
173. 67047287 c.404A>G p.Y135C missense 0.00000824●●●●●●
174. 67047241 c.358G>A p.D120N missense 0.00000824●●●●●●
175. 67062587 c.871G>A p.A291T missense 0.00000824●●●●●●
176. 67040623 c.253G>C p.V85L missense 0.00000824●●●●●●
177. 67039645 c.142A>G p.R48G missense 0.00000824●●●●●●
178. 67066432 c.1387A>G p.S463G missense 0.00000824●●●●●●
179. 67062051 c.775T>A p.S259T missense 0.00000824●●●●●●
180. 67039552 c.49A>G p.M17V missense 0.00000824●●●●●●
181. 67039556 c.53A>G p.D18G missense 0.00000824●●●●●●
182. 67047341 c.458A>G p.H153R missense 0.00000824●●●●●●
183. 67040664 c.294C>A p.N98K missense 0.00000824●●●●●●
184. 67061980 c.704G>T p.R235L missense 0.00000824●●●●●●
185. 67066486 c.1441A>C p.K481Q missense 0.00000824●●●●●●
186. 67066475 c.1430C>G p.S477W missense 0.00000824●●●●●●
187. 67062082 c.806T>C p.M269T missense 0.00000824●●●●●●
188. 67066364 c.1319T>G p.L440W missense 0.00000824●●●●●●
189. 67039597 c.94A>T p.M32L missense 0.00000824●●●●●●
190. 67062665 c.949G>A p.E317K missense 0.00000824●●●●●●
191. 67066388 c.1343G>T p.G448V missense 0.00000824●●●●●●
192. 67039661 c.158A>G p.D53G missense 0.00000824●●●●●●
193. 67062641 c.925C>T p.H309Y missense 0.00000824●●●●●●
194. 67086724 c.1543C>T p.P515S missense 0.00000824●●●●●●
195. 67047242 c.359A>T p.D120V missense 0.00000824●●●●●●
196. 67062012 c.736G>A p.A246T missense 0.00000824●●●●●●
197. 67062596 c.880G>T p.A294S missense 0.00000824●●●●●●
198. 67062054 c.778A>G p.K260E missense 0.00000824●●●●●●
199. 67039646 c.143G>A p.R48K missense 0.00000824●●●●●●
200. 67066438 c.1393G>A p.G465S missense 0.00000824●●●●●●
201. 67062022 c.746A>G p.K249R missense 0.00000824●●●●●●
202. 67039563 c.60A>C p.L20F missense 0.00000824●●●●●●
203. 67047356 c.473T>C p.V158A missense 0.00000824●●●●●●
204. 67086781 c.1600G>C p.A534P missense 0.00000824●●●●●●
205. 67047342 c.459C>G p.H153Q missense 0.00000824●●●●●●
206. 67061989 c.713A>C p.E238A missense 0.00000824●●●●●●
207. 67047254 c.371G>A p.C124Y missense 0.00000824●●●●●●
208. 67086712 c.1531T>C p.F511L missense 0.00000824●●●●●●
209. 67040690 c.320T>A p.I107N missense 0.00000824●●●●●●
210. 67047348 c.465C>G p.D155E missense 0.00000824●●●●●●
211. 67066483 c.1438C>T p.R480W missense 0.00000824●●●●●●
212. 67066417 c.1372C>G p.P458A missense 0.00000824●●●●●●
213. 67062028 c.752A>G p.Y251C missense 0.00000824●●●●●●
214. 67066369 c.1324T>C p.Y442H missense 0.00000824●●●●●●
215. 67066402 c.1357G>T p.A453S missense 0.00000824●●●●●●

* This highlights the relative frequency of the variant in the ExAC populations - Non-Finnish European, African, East Asian, South Asian, American and Finnish. Higher frequencies are denoted by darker shades of green, variants absent in a population are coloured light gray.

✝ Genomic coordinates refer to the GRCh37 release of the human genome.