T-COFFEE, Version_8.99(Thu Feb 17 19:24:49 CET 2011 - Revision 594)
Cedric Notredame
CPU TIME:6 sec.
SCORE=59
*
BAD AVG GOOD
*
KCNH2 : 57
KCNH1 : 62
KCNH3 : 59
KCNH4 : 62
KCNH5 : 59
KCNH6 : 61
KCNH7 : 58
KCNH8 : 59
HCN1 : 54
HCN2 : 55
HCN3 : 61
HCN4 : 51
CNGA1 : 56
CNGA2 : 70
CNGA3 : 68
CNGA4 : 79
CNGB1 : 47
CNGB3 : 55
cons : 59
KCNH2 1 ---MPV--------------------------------------- 3
KCNH1 1 MTMAGG--------------------------------------- 6
KCNH3 1 ---MPA--------------------------------------- 3
KCNH4 1 ---MPV--------------------------------------- 3
KCNH5 1 --MPGG--------------------------------------- 4
KCNH6 1 ---MPV--------------------------------------- 3
KCNH7 1 ---MPV--------------------------------------- 3
KCNH8 1 ---MPV--------------------------------------- 3
HCN1 1 ---MEG--------------------------------------- 3
HCN2 1 ---MDA--------------------------------------- 3
HCN3 1 ---MEA--------------------------------------- 3
HCN4 1 ---MDK--------------------------------------- 3
CNGA1 1 ---MKL--------------------------------------- 3
CNGA2 1 ---MTE--------------------------------------- 3
CNGA3 1 ---MAK--------------------------------------- 3
CNGA4 1 ---MSQ--------------------------------------- 3
CNGB1 1 ---MLGWVQRVLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPN 42
CNGB3 1 --------------------------------------------- 0
cons 1 45
KCNH2 4 ----------------------RR----G-HVAPQNTFLDTI--- 18
KCNH1 7 ----------------------RR----G-LVAPQNTFLENI--- 21
KCNH3 4 ----------------------MR----G-LLAPQNTFLDTI--- 18
KCNH4 4 ----------------------MK----G-LLAPQNTFLDTI--- 18
KCNH5 5 ----------------------KR----G-LVAPQNTFLENI--- 19
KCNH6 4 ----------------------RR----G-HVAPQNTYLDTI--- 18
KCNH7 4 ----------------------RR----G-HVAPQNTFLGTI--- 18
KCNH8 4 ----------------------MK----G-LLAPQNTFLDTI--- 18
HCN1 4 ----------------------G---------------------- 4
HCN2 4 ---------------------------------------RG---- 5
HCN3 4 ----------------------E---------------------- 4
HCN4 4 ----------------------LPPSMRKRLYSLPQQVGAK---- 22
CNGA1 4 ----------------------SMK---NNIINTQQSFVTMPNVI 23
CNGA2 4 ----------------------K--------TNGVK--------S 10
CNGA3 4 -------------------------------INTQY--------S 9
CNGA4 4 --------------------------------------------- 3
CNGB1 43 PEEAETESESMPPEESFKEEEVAV-----ADPSPQETKEAAL--- 79
CNGB3 1 --------------------------------------------- 0
cons 46 90
KCNH2 19 IR----KFEGQSRKF-----------IIANA-RVEN-CAVI-YCN 45
KCNH1 22 VR----RS--NDTNF-----------VLGNA-QIVD-WPIV-YSN 46
KCNH3 19 AT----RFDGTHSNF-----------VLGNA-QVAGLFPVV-YCS 46
KCNH4 19 AT----RFDGTHSNF-----------LLANA-QGTRGFPIV-YCS 46
KCNH5 20 VR----RS--SESSF-----------LLGNA-QIVD-WPVV-YSN 44
KCNH6 19 IR----KFEGQSRKF-----------LIANA-QMEN-CAII-YCN 45
KCNH7 19 IR----KFEGQNKKF-----------IIANA-RVQN-CAII-YCN 45
KCNH8 19 AT----RFDGTHSNF-----------ILANA-QVAKGFPIV-YCS 46
HCN1 5 -------GKPNS--------------------------------- 9
HCN2 6 -G----GGRPGE--------------------------------- 12
HCN3 5 -------QRPAA--------------------------------- 9
HCN4 23 -A----WIMDEE--------------------------------E 30
CNGA1 24 VP----DIEKE------------I----------------R-RME 35
CNGA2 11 SP----AN-----------------------------------NH 16
CNGA3 10 HP----SRTH-------------L----------------KVKTS 21
CNGA4 4 --------------------------------------------- 3
CNGB1 80 TSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIP-QPVH-SIT 122
CNGB3 1 --------------------------------------------- 0
cons 91 135
KCNH2 46 DGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQI-------- 82
KCNH1 47 DGFCKLSGYHRAEVMQKSSTCSFMYGELTDKDTIEKV-------- 83
KCNH3 47 DGFCDLTGFSRAEVMQRGCACSFLYGPDTSELVRQQI-------- 83
KCNH4 47 DGFCELTGYGRTEVMQKTCSCRFLYGPETSEPALQRL-------- 83
KCNH5 45 DGFCKLSGYHRADVMQKSSTCSFMYGELTDKKTIEKV-------- 81
KCNH6 46 DGFCELFGYSRVEVMQQPCTCDFLTGPNTPSSAVSRL-------- 82
KCNH7 46 DGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHDIAQI-------- 82
KCNH8 47 DGFCELAGFARTEVMQKSCSCKFLFGVETNEQLMLQI-------- 83
HCN1 10 --------------------------------------------- 9
HCN2 13 --------------------------------------------- 12
HCN3 10 --------------------------------------------- 9
HCN4 31 DAEEEG-AGGRQDPSRRSIRLRPLPSPSPSAAAGGTESRSSALGA 74
CNGA1 36 N----------------------------------GA-------- 38
CNGA2 17 NHHA------PPA-----------IKANGK-DDHRTS-------- 35
CNGA3 22 D-----------------------RDLNRA-EN--GL-------- 32
CNGA4 4 --------------------------------------------- 3
CNGB1 123 E----------------DPAQILGHGSTGDTGCTDEP-------- 143
CNGB3 1 --------------------------------------------- 0
cons 136 180
KCNH2 83 --------------------------------------------- 82
KCNH1 84 --------------------------------------------- 83
KCNH3 84 --------------------------------------------- 83
KCNH4 84 --------------------------------------------- 83
KCNH5 82 --------------------------------------------- 81
KCNH6 83 --------------------------------------------- 82
KCNH7 83 --------------------------------------------- 82
KCNH8 84 --------------------------------------------- 83
HCN1 10 ---------------------SSN--------------------- 12
HCN2 13 ---------------------SPGATPAPGPPPPPPPAPPQQQPP 36
HCN3 10 -------------------GASEGATP------------------ 17
HCN4 75 ADSEGPARGAGKSSTNGDCRRFRGSLASLGSRGGGSGGTGSGSSH 119
CNGA1 39 --------------------------------------------- 38
CNGA2 36 --------------------------------------------- 35
CNGA3 33 --------------------------------------------- 32
CNGA4 4 --------------------------------------------- 3
CNGB1 144 --------------------------------------------- 143
CNGB3 1 --------------------------------------------- 0
cons 181 225
KCNH2 83 --------------------------------------------- 82
KCNH1 84 --------------------------------------------- 83
KCNH3 84 --------------------------------------------- 83
KCNH4 84 --------------------------------------------- 83
KCNH5 82 --------------------------------------------- 81
KCNH6 83 --------------------------------------------- 82
KCNH7 83 --------------------------------------------- 82
KCNH8 84 --------------------------------------------- 83
HCN1 13 ------------------------------------------SRD 15
HCN2 37 PPPPPAPPPGPGPAPPQHPPRAEALPPEAADEGGPRGRLRSRDSS 81
HCN3 18 ----------------------------------------GLEAV 22
HCN4 120 GHLHDSAEERRLIAEGDASPGEDRTPPGLAAEPERPGASAQPAAS 164
CNGA1 39 --------------------------------------------- 38
CNGA2 36 --------------------------------------------- 35
CNGA3 33 --------------------------------------------- 32
CNGA4 4 --------------------------------------------- 3
CNGB1 144 --------------------------------------------- 143
CNGB3 1 --------------------------------------------- 0
cons 226 270
KCNH2 83 ----------------------------AQALLGAE--------E 91
KCNH1 84 ----------------------------RQTFENYE--------M 92
KCNH3 84 ----------------------------RKALDEHK--------E 92
KCNH4 84 ----------------------------HKALEGHQ--------E 92
KCNH5 82 ----------------------------RQTFDNYE--------S 90
KCNH6 83 ----------------------------AQALLGAE--------E 91
KCNH7 83 ----------------------------AQALLGSE--------E 91
KCNH8 84 ----------------------------EKSLEEKT--------E 92
HCN1 16 DGNSVFPAKASATGAGPAAAEKRLGTPPGGGGAGAK--------E 52
HCN2 82 CGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGP--------A 118
HCN3 23 PPVAPPPA-----------T------------------------- 31
HCN4 165 PPPPQQPPQPAS--------------------------------- 176
CNGA1 39 ----------------------------CSSFSEDDD-SASTSEE 54
CNGA2 36 ----------------------------SRPHSAADDDTSSE--- 49
CNGA3 33 ----------------------------SRAHSSSEE-TSSVLQP 48
CNGA4 4 --------------------------------------------- 3
CNGB1 144 ----------------------------NEALEAQD--------T 152
CNGB3 1 --------------------------------------------- 0
cons 271 315
KCNH2 92 RKVE-IAFYRK-----------DGS-------------------- 104
KCNH1 93 NSFE-ILMYKK-----------NRT-------------------- 105
KCNH3 93 FKAE-LILYRK-----------SGL-------------------- 105
KCNH4 93 HRAE-ICFYRK-----------DGS-------------------- 105
KCNH5 91 NCFE-VLLYKK-----------NRT-------------------- 103
KCNH6 92 CKVD-ILYYRK-----------DAS-------------------- 104
KCNH7 92 RKVE-VTYYHK-----------NGS-------------------- 104
KCNH8 93 FKGE-IMFYKK-----------NGS-------------------- 105
HCN1 53 HGNS-VCFKVD---------------------------------- 62
HCN2 119 RGPK-VSFSCR---------------------------------- 128
HCN3 32 --------------------------------------------- 31
HCN4 177 -------ASCE---------------------------------- 180
CNGA1 55 SENEN-PH-AR-----------GSF-------------------- 66
CNGA2 50 ------LQ-RL-----------ADV-------------------- 56
CNGA3 49 GIAME-TR-GL-----------ADS-------------------- 60
CNGA4 4 --------------------------------------------- 3
CNGB1 153 RPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPP 197
CNGB3 1 --------------------------------------------- 0
cons 316 360
KCNH2 105 CFLCLVDVV------------------------------------ 113
KCNH1 106 PVWFFVKIA------------------------------------ 114
KCNH3 106 PFWCLLDVI------------------------------------ 114
KCNH4 106 AFWCLLDMM------------------------------------ 114
KCNH5 104 PVWFYMQIA------------------------------------ 112
KCNH6 105 SFRCLVDVV------------------------------------ 113
KCNH7 105 TFICNTHII------------------------------------ 113
KCNH8 106 PFWCLLDIV------------------------------------ 114
HCN1 63 --------------------------------------------- 62
HCN2 129 --------------------------------------------- 128
HCN3 32 --------------------------------------------- 31
HCN4 181 --------------------------------------------- 180
CNGA1 67 SYKSLRKG-G----------------------------------- 75
CNGA2 57 D-APQQGRSG----------------------------------- 65
CNGA3 61 GQGSFTGQ-G----------------------------------- 69
CNGA4 4 --------------------------------------------- 3
CNGB1 198 GRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQ 242
CNGB3 1 --------------------------------------------- 0
cons 361 405
KCNH2 114 --------------------------------PVK---NEDGAVI 123
KCNH1 115 --------------------------------PIR---NEQDKVV 124
KCNH3 115 --------------------------------PIK---NEKGEVA 124
KCNH4 115 --------------------------------PIK---NEMGEVV 124
KCNH5 113 --------------------------------PIR---NEHEKVV 122
KCNH6 114 --------------------------------PVK---NEDGAVI 123
KCNH7 114 --------------------------------PVK---NQEGVAM 123
KCNH8 115 --------------------------------PIK---NEKGDVV 124
HCN1 63 ----------------------------------------GG--- 64
HCN2 129 ----------------------------------------GA--- 130
HCN3 32 -----------------------------------------A--- 32
HCN4 181 ----------------------------------------QP--- 182
CNGA1 76 --------------------------------PSQREQYLPGAIA 88
CNGA2 66 ---------------------------------FRRIVRLVGIIR 77
CNGA3 70 ---------------------------------IARLSRLIFLLR 81
CNGA4 4 --------------------------------------------- 3
CNGB1 243 TSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIG---EQEPDSP 284
CNGB3 1 --------------------------------------------- 0
cons 406 450
KCNH2 124 MFILNFEVVMEKDM-VG---------------------------- 139
KCNH1 125 LFLCTFSDITAFKQ-PI---------------------------- 140
KCNH3 125 LFLVSHKDISETK-NRG---------------------------- 140
KCNH4 125 LFLFSFKDITQSGSPGL---------------------------- 141
KCNH5 123 LFLCTFKDITLFKQ-PI---------------------------- 138
KCNH6 124 MFILNFEDLAQL--------------------------------- 135
KCNH7 124 MFIINFEYVTDNEN-AA---------------------------- 139
KCNH8 125 LFLASFKDITDTK-VKI---------------------------- 140
HCN1 65 ---------GGGGG-GGG--------------------------- 72
HCN2 131 ---------ASGPA-PGP--------------------------- 138
HCN3 33 ---------ASGPI-PKS--------------------------- 40
HCN4 183 ---------SVDTA-IKV--------------------------- 190
CNGA1 89 LFNVNNSSNKDQ--------------------------------- 100
CNGA2 78 EWANKNFREEEP--------------------------------- 89
CNGA3 82 RWAARHVHHQDQ--------------------------------- 93
CNGA4 4 ----------DT--------------------------------- 5
CNGB1 285 GICDVQTISILPGG---QVEPDLVLEEVEPPWEDAHQDVSTSPQG 326
CNGB3 1 --------------------------------------------- 0
cons 451 495
KCNH2 140 ----------------SPAH------------------------- 143
KCNH1 141 ----------------EDDS------------------------- 144
KCNH3 141 ----------------GPDR------------------------- 144
KCNH4 142 ----------------GPQG------------------------- 145
KCNH5 139 ----------------EDDS------------------------- 142
KCNH6 136 --------------------------------------------- 135
KCNH7 140 ----------------TPER------------------------- 143
KCNH8 141 ----------------TPE-------------------------- 143
HCN1 73 ----------------GGEE------------------------- 76
HCN2 139 ----------------GPAE------------------------- 142
HCN3 41 ----------------GPE-------------------------- 43
HCN4 191 ----------------EGGA------------------------- 194
CNGA1 101 ----------------EPEE------------------------- 104
CNGA2 90 ----------------RPDS------------------------- 93
CNGA3 94 ----------------GPDS------------------------- 97
CNGA4 6 --------------------------------------------- 5
CNGB1 327 TEVVPAYEEENKAVEKMPRELSRIEEEKEDEEEEEEEEEEEEEEE 371
CNGB3 1 ----------------MFKSLTKVNKVKPIGENNENEQS------ 23
cons 496 540
KCNH2 144 ----------DTNHRGPPTSWLAPGRAKTFRLKLPALLALTARES 178
KCNH1 145 --------------------------CKGWG-------------- 149
KCNH3 145 ----------W----------------KETGGGRR---------- 153
KCNH4 146 ----------G----------------RGDSNHEN---------- 154
KCNH5 143 --------------------------TKGWT-------------- 147
KCNH6 136 ---------------------LAKCSSRSLSQRLLSQSFLGSEGS 159
KCNH7 144 ----------V-N----PILPIKTVNRKFFGFKFPGLRVLTYRKQ 173
KCNH8 144 -----------------------------DKKEDK---------- 149
HCN1 77 --------------------PA------GG---F----------- 81
HCN2 143 --------------------EA------GSEEAG----------- 150
HCN3 44 --------------------------------------------- 43
HCN4 195 ---------------------A------AGDQIL----------- 201
CNGA1 105 --------------------------------------------- 104
CNGA2 94 --------------------------------------------- 93
CNGA3 98 --------------------------------------------- 97
CNGA4 6 --------------------------------------------- 5
CNGB1 372 VTEVLLDSCVVSQVGVGQSEEDGTRPQSTSDQKLWEEVGEEAKKE 416
CNGB3 24 ----------------SRRNEEGSHPSNQSQQ----TTAQEENKG 48
cons 541 585
KCNH2 179 SVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVA 223
KCNH1 150 --------------------------------------------- 149
KCNH3 154 --------------------------------------------- 153
KCNH4 155 --------------------------------------------- 154
KCNH5 148 --------------------------------------------- 147
KCNH6 160 HGRPGGPG------------------------------------- 167
KCNH7 174 SLPQEDPD------VVVIDS----SKHSDDSVAMKHFKSPTKESC 208
KCNH8 150 --------------------------------------------- 149
HCN1 82 --------------------------------------------- 81
HCN2 151 --------------------------------------------- 150
HCN3 44 --------------------------------------------- 43
HCN4 202 --------------------------------------------- 201
CNGA1 105 --------------------------------------------- 104
CNGA2 94 --------------------------------------------- 93
CNGA3 98 --------------------------------------------- 97
CNGA4 6 --------------------------------------------- 5
CNGB1 417 AEEKAKEEAEEVAEEEAEKEPQDWAETKEEPEAEAEAASSGVPAT 461
CNGB3 49 EEKSLKTKSTPVTSEEPHTNIQDKLSKKN---------SSGDLTT 84
cons 586 630
KCNH2 224 GLGPAEE---------------RRALV--GPGSP--PRSA--PGQ 247
KCNH1 150 --------------------------------------------- 149
KCNH3 154 --------------------------------------------- 153
KCNH4 155 --------------------------------------------- 154
KCNH5 148 --------------------------------------------- 147
KCNH6 168 ---PG---------------------------------------- 169
KCNH7 209 SPSEADD---------------TKALI--QPSKCSPLVNISGPLD 236
KCNH8 150 --------------------------------------------- 149
HCN1 82 --------------------------------------------- 81
HCN2 151 --------------------------------------------- 150
HCN3 44 --------------------------------------------- 43
HCN4 202 --------------------------------------------- 201
CNGA1 105 --------------------------------------------- 104
CNGA2 94 --------------------------------------------- 93
CNGA3 98 --------------------------------------------- 97
CNGA4 6 --------------------------------------------- 5
CNGB1 462 KQHPEVQVEDTDADSCPLMAEENPPSTVLPPPSPA---K------ 497
CNGB3 85 NPDPQNA-------------------------------A------ 92
cons 631 675
KCNH2 248 L--PSPRAHSLNPDASGSS------CSL----ARTRSRESCASVR 280
KCNH1 150 --------------------------------------------- 149
KCNH3 154 --------------------------RY----GRAR--------- 159
KCNH4 155 --------------------------SL----GRRG--------- 160
KCNH5 148 --------------------------------------------- 147
KCNH6 170 --------------------------------------------- 169
KCNH7 237 HSSPKRQWDRLYPDMLQSS------SQL----SHSRSRESLCSIR 271
KCNH8 150 --------------------------VK----GRSR--------- 155
HCN1 82 ---------------------------------E----------- 82
HCN2 151 ---------------------------------P----------- 151
HCN3 44 --------------------------------------------- 43
HCN4 202 ---------------------------------P----------- 202
CNGA1 105 --------------------------------------------- 104
CNGA2 94 --------------------------------------------- 93
CNGA3 98 --------------------------------------------- 97
CNGA4 6 --------------------------------------------- 5
CNGB1 498 ------------SDTLIVPSSASGTHRKKLPSEDDEA-E------ 523
CNGB3 93 ------------EPTGTVP-------------------------- 99
cons 676 720
KCNH2 281 RASSADDIEAM-------------RAGVLPPPPRHASTGAMHPLR 312
KCNH1 150 --------------------------------------------- 149
KCNH3 160 --------------------------------------------- 159
KCNH4 161 --------------------------------------------- 160
KCNH5 148 --------------------------------------------- 147
KCNH6 170 --------------------------------------------- 169
KCNH7 272 RASSVHDIEGFGV-----HPKNIFRDRHASEDNGRNVKGPFNHIK 311
KCNH8 156 --------------------------------------------- 155
HCN1 83 --------------------------------------------- 82
HCN2 152 --------------------------------------------- 151
HCN3 44 --------------------------------------------- 43
HCN4 203 --------------------------------------------- 202
CNGA1 105 --------------------------------------------- 104
CNGA2 94 --------------------------------------------- 93
CNGA3 98 --------------------------------------------- 97
CNGA4 6 --------------------------------------------- 5
CNGB1 524 ---ELKALSPAESPVVAWS-----DPTTPKDTDGQDRAASTASTN 560
CNGB3 100 ---EQKEMDPGKE-----------GPNSPQNK------PPAAPVI 124
cons 721 765
KCNH2 313 SGLLNSTSDSDLVRYR---TISKIPQITLNFVDLKGDPFLASP-T 353
KCNH1 150 -------------KFA------------------RLTRALTSS-R 162
KCNH3 160 --------------S----K--------------GFNANRRRS-R 171
KCNH4 161 --------------AT---W--------------KFRSARRRS-R 173
KCNH5 148 -------------KFA------------------RLTRALTNS-R 160
KCNH6 170 ---------TGRGKYR---TISQIPQFTLNFVEFNLEKHRSSS-T 201
KCNH7 312 SSLLGSTSDSNLNKYS---TINKIPQLTLNFSEVKTEKKNSSPPS 353
KCNH8 156 --------------AG---T--------------HFDSARRRS-R 168
HCN1 83 -----------------------------------DAEGPR-R-Q 90
HCN2 152 -----------------------------------AGEPRG-S-Q 159
HCN3 44 --------------------------------------------- 43
HCN4 203 -----------------------------------EAEVRL-G-Q 210
CNGA1 105 --------------KK---K-------------K-KKEKKSKS-D 117
CNGA2 94 --------------FL---E-------------R-FRGPELQT-V 106
CNGA3 98 --------------FP---D-------------R-FRGAELKE-V 110
CNGA4 6 ---------------------------------------KVKT-T 10
CNGB1 561 SAIINDRLQELVKLFKERTEKV-KEKLIDPDVTSDEE-SPKPSPA 603
CNGB3 125 NEYADAQLHNLVKRMRQRTALY-KKKLVEGDLSS-----PEASPQ 163
cons 766 810
KCNH2 354 -SDREIIA-P-KIK-E--R--TH--NVTEKVTQVLSLGADV-L-P 386
KCNH1 163 -GVLQQLA-PS-VQKG--E--NV--HKHSRLAEVLQLGSDI-L-P 196
KCNH3 172 -AVLYHLS-GH-LQK---Q--PK--G-KHKLNKGVFGEKPN-L-P 203
KCNH4 174 -TVLHRLT-GH-FGR---R--GQ--G-GMKANNNVFEPKPS-V-P 205
KCNH5 161 -SVLQQLT-PM-NKT---E--VV--HKHSRLAEVLQLGSDI-L-P 193
KCNH6 202 -TEIEIIA-PHKVV-E--R--TQ--NVTEKVTQVLSLGADV-L-P 235
KCNH7 354 -SDKTIIA-P-KVK-D--R--TH--NVTEKVTQVLSLGADV-L-P 386
KCNH8 169 -AVLYHIS-GH-LQR---R--EK--N-KLKINNNVFVDKPA-F-P 200
HCN1 91 YGFMQRQF--T-SM----L--QP--GVNKF-SLRMFGSQKA-V-E 121
HCN2 160 ASFMQRQF--G-AL----L--QP--GVNKF-SLRMFGSQKA-V-E 190
HCN3 44 --PKRRHL--G-TL----L--QP--TVNKF-SLRVFGSHKA-V-E 72
HCN4 211 AGFMQRQF--G-AM----L--QP--GVNKF-SLRMFGSQKA-V-E 241
CNGA1 118 -DKNENKNDPE-KKK---KK--------K-D-KEKKKK--E-EK- 143
CNGA2 107 -TTQEGDGKG--D-----------------------------KD- 118
CNGA3 111 -SSQESNAQ-A-NVG---SQEPADRGR-S-AWPLAKCNTNTSNNT 147
CNGA4 11 -ES------------------------------------------ 12
CNGB1 604 -KKAPEPA-PD-TKPAEAE--PV--EEEHYCDM-LCCKFKH-R-P 638
CNGB3 164 -TAKPTAV-PP-VKES--D--DK--PTEHYYRL-LWFKVKK-M-P 196
cons 811 855
KCNH2 387 -EYKLQAPRIHRWTILHYSPFKA-VWDWLILLLVIYTAVFTPYSA 429
KCNH1 197 -QYKQEAPKTPPHIILHYCVFKT-TWDWIILILTFYTAILVPYNV 239
KCNH3 204 -EYKVAAIRKSPFILLHCGALRA-TWDGFILLATLYVAVTVPYSV 246
KCNH4 206 -EYKVASVGGSRCLLLHYSVSKA-IWDGLILLATFYVAVTVPYNV 248
KCNH5 194 -QYKQEAPKTPPHIILHYCAFKT-TWDWVILILTFYTAIMVPYNV 236
KCNH6 236 -EYKLQAPRIHRWTILHYSPFKA-VWDWLILLLVIYTAVFTPYSA 278
KCNH7 387 -EYKLQTPRINKFTILHYSPFKA-VWDWLILLLVIYTAIFTPYSA 429
KCNH8 201 -EYKVSDAKKSKFILLHFSTFKA-GWDWLILLATFYVAVTVPYNV 243
HCN1 122 -KEQERVKTAGFWIIHPYSDFRF-YWDLIMLIMMVGNLVIIPVGI 164
HCN2 191 -REQERVKSAGAWIIHPYSDFRF-YWDFTMLLFMVGNLIIIPVGI 233
HCN3 73 -IEQERVKSAGAWIIHPYSDFRF-YWDLIMLLLMVGNLIVLPVGI 115
HCN4 242 -REQERVKSAGFWIIHPYSDFRF-YWDLTMLLLMVGNLIIIPVGI 284
CNGA1 144 SKDKKEEEKKEVVVIDPSGNTYY-NWLFCITLPVMYNWTMVIARA 187
CNGA2 119 GEDKGTKKKFELFVLDPAGDWYY-CWLFVIAMPVLYNWCLLVARA 162
CNGA3 148 EEE-KKTKKKDAIVVDPSSNLYY-RWLTAIALPVFYNWYLLICRA 190
CNGA4 13 SPPAPSKARKLLPVLDPSGDYYY-WWLNTMVFPVMYNLIILVCRA 56
CNGB1 639 -W----KKYQFPQSIDPLTNLMYVLWLFFVVMAWNWNCWLIPVRW 678
CNGB3 197 -LTEYLKRIKLPNSIDSYTDRLYLLWLLLVTLAYNWNCCFIPLRL 240
cons 856 : * : : 900
KCNH2 430 AFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDI-LINFRT 473
KCNH1 240 SFKTRQN------------NVAWLVVDSIVDVIFLVDI-VLNFHT 271
KCNH3 247 CVSTARE--------PSAARGPPSVCDLAVEVLFILDI-VLNFRT 282
KCNH4 249 CFSGDDD--------TPITSRHTLVSDIAVEMLFILDI-ILNFRT 284
KCNH5 237 SFKTKQN------------NIAWLVLDSVVDVIFLVDI-VLNFHT 268
KCNH6 279 AFLLSDQDE-SRRGACSYTCSPLTVVDLIVDIMFVVDI-VINFRT 321
KCNH7 430 AFLLNDREE-QKRRECGYSCSPLNVVDLIVDIMFIIDI-LINFRT 472
KCNH8 244 CFIGNDD--------LS-TTRSTTVSDIAVEILFIIDI-ILNFRT 278
HCN1 165 TFFTEQT------------TTPWIIFNVASDTVFLLDL-IMNFRT 196
HCN2 234 TFFKDET------------TAPWIVFNVVSDTFFLMDL-VLNFRT 265
HCN3 116 TFFKEEN------------SPPWIVFNVLSDTFFLLDL-VLNFRT 147
HCN4 285 TFFKDEN------------TTPWIVFNVVSDTFFLIDL-VLNFRT 316
CNGA1 188 CFDELQS----------DYLEYWLILDYVSDIVYLIDM-FVRTRT 221
CNGA2 163 CFSDLQK----------GYYLVWLVLDYVSDVVYIADL-FIRLRT 196
CNGA3 191 CFDELQS----------EYLMLWLVLDYSADVLYVLDV-LVRART 224
CNGA4 57 CFPDLQH----------GYLVAWLVLDYTSDLLYLLDM-VVRFHT 90
CNGB1 679 AFPYQTP----------DNIHHWLLMDYLCDLIYFLDITVFQTRL 713
CNGB3 241 VFPYQTA----------DNIHYWLIADIICDIIYLYDMLFIQPRL 275
cons 901 . : : : .:. *: ... : 945
KCNH2 474 TYVN-ANEEVVSHPGRIAVHYFKGW-FLIDMVAAIPFDLLIFGSG 516
KCNH1 272 TFVG-PAGEVISDPKLIRMNYLKTW-FVIDLLSCLPYDVINAFEN 314
KCNH3 283 TFVS-KSGQVVFAPKSICLHYVTTW-FLLDVIAALPFDLLHAF-K 324
KCNH4 285 TYVS-QSGQVISAPRSIGLHYLATW-FFIDLIAALPFDLLYIF-N 326
KCNH5 269 TFVG-PGGEVISDPKLIRMNYLKTW-FVIDLLSCLPYDIINAFEN 311
KCNH6 322 TYVN-TNDEVVSHPRRIAVHYFKGW-FLIDMVAAIPFDLLIFRTG 364
KCNH7 473 TYVN-QNEEVVSDPAKIAIHYFKGW-FLIDMVAAIPFDLLIFGSG 515
KCNH8 279 TYVS-KSGQVIFEARSICIHYVTTW-FIIDLIAALPFDLLYAF-N 320
HCN1 197 GTVNEDSSEIILDPKVIKMNYLKSW-FVVDFISSIPVDYIFLIVE 240
HCN2 266 GIVIEDNTEIILDPEKIKKKYLRTW-FVVDFVSSIPVDYIFLIVE 309
HCN3 148 GIVVEEGAEILLAPRAIRTRYLRTW-FLVDLISSIPVDYIFLVVE 191
HCN4 317 GIVVEDNTEIILDPQRIKMKYLKSW-FMVDFISSIPVDYIFLIVE 360
CNGA1 222 GYLE--QGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLG 264
CNGA2 197 GFLE--QGLLVKDTKKLRDNYIHTLQFKLDVASIIPTDLIYFAVD 239
CNGA3 225 GFLE--QGLMVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAYLKVG 267
CNGA4 91 GFLE--QGILVVDKGRISSRYVRTWSFFLDLASLMPTDVVYVRLG 133
CNGB1 714 QFVR--GGDIITDKKDMRNNYLKSRRFKMDLLSLLPLDFLYLKVG 756
CNGB3 276 QFVR--GGDIIVDSNELRKHYRTSTKFQLDVASIIPFDICYLFFG 318
cons 946 : :: : .* * :*. : :* * 990
KCNH2 517 SEE----------------------------------LIGLLKTA 527
KCNH1 315 VDEVSAFMGDPGKIGFADQ---IPPPLEGRESQGISSLFSSLKVV 356
KCNH3 325 VN----------------V---Y-------------FGAHLLKTV 337
KCNH4 327 IT----------------V---T-------------SLVHLLKTV 339
KCNH5 312 VDEG------------------------------ISSLFSSLKVV 326
KCNH6 365 SDE---------------T---T-------------TLIGLLKTA 378
KCNH7 516 SDE---------------T---T-------------TLIGLLKTA 529
KCNH8 321 VT----------------V---V-------------SLVHLLKTV 333
HCN1 241 K--GMDSEVYKTARALR-IVRFT-------------KILSLLRLL 269
HCN2 310 K--GIDSEVYKTARALR-IVRFT-------------KILSLLRLL 338
HCN3 192 LEPRLDAEVYKTARALR-IVRFT-------------KILSLLRLL 222
HCN4 361 T--RIDSEVYKTARALR-IVRFT-------------KILSLLRLL 389
CNGA1 265 WNY---------------------------------PEIRLNRLL 276
CNGA2 240 IHS---------------------------------PEVRFNRLL 251
CNGA3 268 TNY---------------------------------PEVRFNRLL 279
CNGA4 134 PHT---------------------------------PTLRLNRFL 145
CNGB1 757 VN----------------------------------PLLRLPRCL 767
CNGB3 319 FN----------------------------------PMFRANRML 329
cons 991 : 1035
KCNH2 528 RLLRLVRVARKLDRY-----SEYGAAV-LFLLMCTFALIAHWLAC 566
KCNH1 357 RLLRLGRVARKLDHY-----IEYGAAV-LVLLVCVFGLAAHWMAC 395
KCNH3 338 RLLRLLRLLPRLDRY-----SQYSAVV-LTLLMAVFALLAHWVAC 376
KCNH4 340 RLLRLLRLLQKLERY-----SQCSAVV-LTLLMSVFALLAHWMAC 378
KCNH5 327 RLLRLGRVARKLDHY-----LEYGAAV-LVLLVCVFGLVAHWLAC 365
KCNH6 379 RLLRLVRVARKLDRY-----SEYGAAV-LFLLMCTFALIAHWLAC 417
KCNH7 530 RLLRLVRVARKLDRY-----SEYGAAV-LMLLMCIFALIAHWLAC 568
KCNH8 334 RLLRLLRLLQKLDRY-----SQHSTIV-LTLLMSMFALLAHWMAC 372
HCN1 270 RLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGC 314
HCN2 339 RLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGC 383
HCN3 223 RLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGC 267
HCN4 390 RLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGC 434
CNGA1 277 RFSRMFEFFQRTETR-----TNYPNIFRISNLVMYIVIIIHWNAC 316
CNGA2 252 HFARMFEFFDRTETR-----TNYPNIFRISNLVLYILVIIHWNAC 291
CNGA3 280 KFSRLFEFFDRTETR-----TNYPNMFRIGNLVLYILIIIHWNAC 319
CNGA4 146 RAPRLFEAFDRTETR-----TAYPNAFRIAKLMLYIFVVIHWNSC 185
CNGB1 768 KYMAFFEFNSRLESI-----LSKAYVYRVIRTTAYLLYSLHLNSC 807
CNGB3 330 KYTSFFEFNHHLESI-----MDKAYIYRVIRTTGYLLFILHINAC 369
cons 1036 : : . : : : : * .* 1080
KCNH2 567 IWYAIGNMEQPHMDSR----IGWLHNLGDQIGKPYNSS------- 600
KCNH1 396 IWYSIGDYEIFDEDTKTIRNNSWLYQLAMDIGTPYQFN------- 433
KCNH3 377 VWFYIGQREIESSESELPE-IGWLQELARRLETPYYLVGRRPAGG 420
KCNH4 379 IWYVIGRREMEANDPLLWD-IGWLHELGKRLEVPYVNG------- 415
KCNH5 366 IWYSIGDYEVIDEVTNTIQIDSWLYQLALSIGTPYRYN------- 403
KCNH6 418 IWYAIGNVERPYLEHK----IGWLDSLGVQLGKRYNGS------- 451
KCNH7 569 IWYAIGNVERPYLTDK----IGWLDSLGQQIGKRYNDS------- 602
KCNH8 373 IWYVIGKMEREDNSLLKWE-VGWLHELGKRLESPYYGNN------ 410
HCN1 315 LQFLVPLLQDFPPD-------CWVS-----LNEM----------- 336
HCN2 384 LQFLVPMLQDFPRN-------CWVS-----INGM----------- 405
HCN3 268 LQFLVPMLQDFPPD-------CWVS-----INHM----------- 289
HCN4 435 LQFLVPMLQDFPDD-------CWVS-----INNM----------- 456
CNGA1 317 VFYSISKAIGFGND-------TWVYPD---INDP----------- 340
CNGA2 292 IYYAISKSIGFGVD-------TWVYPN---ITDP----------- 315
CNGA3 320 IYFAISKFIGFGTD-------SWVYPN---ISIP----------- 343
CNGA4 186 LYFALSRYLGFGRD-------AWVYPD---PAQP----------- 209
CNGB1 808 LYYWASAYQGLGST-------HWVYD------------------- 826
CNGB3 370 VYYWASNYEGIGTT-------RWVYD------------------- 388
cons 1081 : : *: 1125
KCNH2 601 ---G------------------LGGPSIKDKYVTALYFTFSSLTS 624
KCNH1 434 -GSG-----------S--GK-WEGGPSKNSVYISSLYFTMTSLTS 463
KCNH3 421 NSSGQSDNCSSSSEANGTGLELLGGPSLRSAYITSLYFALSSLTS 465
KCNH4 416 ---------------------SVGGPSRRSAYIAALYFTLSSLTS 439
KCNH5 404 -T-S-----------A--GI-WEGGPSKDSLYVSSLYFTMTSLTT 432
KCNH6 452 ---D-----------P------ASGPSVQDKYVTALYFTFSSLTS 476
KCNH7 603 ---D-----------S------SSGPSIKDKYVTALYFTFSSLTS 627
KCNH8 411 ---------------------TLGGPSIRSAYIAALYFTLSSLTS 434
HCN1 337 -----------------------VNDSWGKQYSYALFKAMSHMLC 358
HCN2 406 -----------------------VNHSWSELYSFALFKAMSHMLC 427
HCN3 290 -----------------------VNHSWGRQYSHALFKAMSHMLC 311
HCN4 457 -----------------------VNNSWGKQYSYALFKAMSHMLC 478
CNGA1 341 -----------------------EFGRLARKYVYSLYWSTLTLTT 362
CNGA2 316 -----------------------EYGYLAREYIYCLYWSTLTLTT 337
CNGA3 344 -----------------------EHGRLSRKYIYSLYWSTLTLTT 365
CNGA4 210 -----------------------GFERLRRQYLYSFYFSTLILTT 231
CNGB1 827 --------------------------GVGNSYIRCYYFAVKTLIT 845
CNGB3 389 --------------------------GEGNEYLRCYYWAVRTLIT 407
cons 1126 * . : : : 1170
KCNH2 625 VGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 669
KCNH1 464 VGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYAN 508
KCNH3 466 VGFGNVSANTDTEKIFSICTMLIGALMHAVVFGNVTAIIQRMYAR 510
KCNH4 440 VGFGNVCANTDAEKIFSICTMLIGALMHAVVFGNVTAIIQRMYSR 484
KCNH5 433 IGFGNIAPTTDVEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYAN 477
KCNH6 477 VGFGNVSPNTNSEKVFSICVMLIGSLMYASIFGNVSAIIQRLYSG 521
KCNH7 628 VGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 672
KCNH8 435 VGFGNVSANTDAEKIFSICTMLIGALMHALVFGNVTAIIQRMYSR 479
HCN1 359 IGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSS 403
HCN2 428 IGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSS 472
HCN3 312 IGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSS 356
HCN4 479 IGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSS 523
CNGA1 363 IG-ETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAA 406
CNGA2 338 IG-ETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNAT 381
CNGA3 366 IG-ETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNAS 409
CNGA4 232 VG-DTPPPAREEEYLFMVGDFLLAVMGFATIMGSMSSVIYNMNTA 275
CNGB1 846 IG-GLPDPKTLFEIVFQLLNYFTGVFAFSVMIGQMRDVVGAATAG 889
CNGB3 408 IG-GLPEPQTLFEIVFQLLNFFSGVFVFSSLIGQMRDVIGAATAN 451
cons 1171 :* . : : : : . .: ..* :. : 1215
KCNH2 670 TARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMN 714
KCNH1 509 TNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTE 553
KCNH3 511 RFLYHSRTRDLRDYIRIHRIPKPLKQRMLEYFQATWAVNNGIDTT 555
KCNH4 485 RSLYHSRMKDLKDFIRVHRLPRPLKQRMLEYFQTTWAVNSGIDAN 529
KCNH5 478 TNRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTE 522
KCNH6 522 TARYHTQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMN 566
KCNH7 673 TARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMN 717
KCNH8 480 WSLYHTRTKDLKDFIRVHHLPQQLKQRMLEYFQTTWSVNNGIDSN 524
HCN1 404 RRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQG-KIFDEE 447
HCN2 473 RRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQG-KMFDED 516
HCN3 357 RRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQG-KMFDEE 400
HCN4 524 RRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQG-KMFDEE 567
CNGA1 407 RAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEK 451
CNGA2 382 RAEFQAKIDAVKHYMQFRKVSKGMEAKVIRWFDYLWTNKKTVDER 426
CNGA3 410 RAEFQAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEK 454
CNGA4 276 DAAFYPDHALVKKYMKLQHVNRKLERRVIDWYQHLQINKKMTNEV 320
CNGB1 890 QTYYRSCMDSTVKYMNFYKIPKSVQNRVKTWYEYTWHSQGMLDES 934
CNGB3 452 QNYFRACMDDTIAYMNNYSIPKLVQKRVRTWYEYTWDSQRMLDES 496
cons 1216 : :: : :: : : 1260
KCNH2 715 AVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFK 759
KCNH1 554 KVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQ 598
KCNH3 556 ELLQSLPDELRADIAMHLHKEVL-QLPLFEAASRGCLRALSLALR 599
KCNH4 530 ELLRDFPDELRADIAMHLNREIL-QLPLFGAASRGCLRALSLHIK 573
KCNH5 523 KVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALAVEFQ 567
KCNH6 567 AVLKGFPECLQADICLHLHRALLQHCPAFSGAGKGCLRALAVKFK 611
KCNH7 718 MVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFK 762
KCNH8 525 ELLKDFPDELRSDITMHLNKEIL-QLSLFECASRGCLRSLSLHIK 568
HCN1 448 NILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLR 492
HCN2 517 SILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLK 561
HCN3 401 SILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLR 445
HCN4 568 SILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLR 612
CNGA1 452 EVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQ 496
CNGA2 427 EILKNLPAKLRAEIAINVHLSTLKKVRIFHDCEAGLLVELVLKLR 471
CNGA3 455 EVLKSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLR 499
CNGA4 321 AILQHLPERLRAEVAVSVHLSTLSRVQIFQNCEASLLEELVLKLQ 365
CNGB1 935 ELMVQLPDKMRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLR 979
CNGB3 497 DLLKTLPTTVQLALAIDVNFSIISKVDLFKGCDTQMIYDMLLRLK 541
cons 1261 :: :: : . * . : : :: 1305
KCNH2 760 TTHAPPGDTLVHAGDLLTALYFISRGSIEILRG-D--VVVAILGK 801
KCNH1 599 TVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQD-D--EVVAILGK 640
KCNH3 600 PAFCTPGEYLIHQGDALQALYFVCSGSMEVLKG-G--TVLAILGK 641
KCNH4 574 TSFCAPGEYLLRRGDALQAHYYVCSGSLEVLRD-N--MVLAILGK 615
KCNH5 568 TIHCAPGDLIYHAGESVDALCFVVSGSLEVIQD-D--EVVAILGK 609
KCNH6 612 TTHAPPGDTLVHLGDVLSTLYFISRGSIEILRD-D--VVVAILGK 653
KCNH7 763 TTHAPPGDTLVHCGDVLTALYFLSRGSIEILKD-D--IVVAILGK 804
KCNH8 569 TSFCAPGEYLLRQGDALQAIYFVCSGSMEVLKD-S--MVLAILGK 610
HCN1 493 FEVFQPGDYIIREGAVGKKMYFIQHGVAGVITK-S--SKEMKLTD 534
HCN2 562 FEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-G--NKEMKLSD 603
HCN3 446 FEVFQPGDLVVREGSVGRKMYFIQHGLLSVLAR-G--ARDTRLTD 487
HCN4 613 FEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-G--NKETKLAD 654
CNGA1 497 PQVYSPGDYICKKGDIGREMYIIKEGKLAVVAD-DGVTQFVVLSD 540
CNGA2 472 PQVFSPGDYICRKGDIGKEMYIIKEGKLAVVAD-DGVTQYALLSA 515
CNGA3 500 PTVFSPGDYICKKGDIGKEMYIINEGKLAVVAD-DGVTQFVVLSD 543
CNGA4 366 PQTYSPGEYVCRKGDIGQEMYIIREGQLAVVAD-DGITQYAVLGA 409
CNGB1 980 SVVYLPNDYVCKKGEIGREMYIIQAGQVQVLGGPDGKSVLVTLKA 1024
CNGB3 542 SVLYLPGDFVCKKGEIGKEMYIIKHGEVQVLGGPDGTKVLVTLKA 586
cons 1306 *.: : : * : * :: . * 1350
KCNH2 802 NDIFGEPLNLYAR------P----GKSNGDVRALTYCDLHKIHRD 836
KCNH1 641 GDVFGDVFWKEAT------L----AQSCANVRALTYCDLHVIKRD 675
KCNH3 642 GDLIGCELPRREQ------V----VKANADVKGLTYCVLQCLQLA 676
KCNH4 616 GDLIGADIPEPGQEPGLGADPNFVLKTSADVKALTYCGLQQLSSR 660
KCNH5 610 GDVFGDIFWKETT------L----AHACANVRALTYCDLHIIKRE 644
KCNH6 654 NDIFGEPVSLHAQ------P----GKSSADVRALTYCDLHKIQRA 688
KCNH7 805 NDIFGEMVHLYAK------P----GKSNADVRALTYCDLHKIQRE 839
KCNH8 611 GDLIGANLSIKDQ------V----IKTNADVKALTYCDLQCIILK 645
HCN1 535 GSYFGEICLLTKG------------RRTASVRADTYCRLYSLSVD 567
HCN2 604 GSYFGEICLLTRG------------RRTASVRADTYCRLYSLSVD 636
HCN3 488 GSYFGEICLLTRG------------RRTASVRADTYCRLYSLSVD 520
HCN4 655 GSYFGEICLLTRG------------RRTASVRADTYCRLYSLSVD 687
CNGA1 541 GSYFGEISILNIKGSKA--G----NRRTANIKSIGYSDLFCLSKD 579
CNGA2 516 GSCFGEISILNIKGSKM--G----NRRTANIRSLGYSDLFCLSKD 554
CNGA3 544 GSYFGEISILNIKGSKS--G----NRRTANIRSIGYSDLFCLSKD 582
CNGA4 410 GLYFGEISIINIKGNMS--G----NRRTANIKSLGYSDLFCLSKE 448
CNGB1 1025 GSVFGEISLLAVGG-----G----NRRTANVVAHGFTNLFILDKK 1060
CNGB3 587 GSVFGEISLLAAGG-----G----NRRTANVVAHGFANLLTLDKK 622
cons 1351 . :* : ..: . : * : 1395
KCNH2 837 DLLEVLDMYPEFSDHFWSSL--EIT-FNLRDTNM-IP-GSP---G 873
KCNH1 676 ALQKVLEFYTAFSHSFSRNL--ILT-YNLRKRIV-FRKISD-V-- 713
KCNH3 677 GLHDSLALYPEFAPRFSRGLRGELS-YNLGAGGG-SAEVDT-S-- 716
KCNH4 661 GLAEVLRLYPEYGAAFRAGLPRDLT-FNLRQGSD-TSGLSR-F-- 700
KCNH5 645 ALLKVLDFYTAFANSFSRNL--TLT-CNLRKRII-FRKISD-V-- 682
KCNH6 689 DLLEVLDMYPAFAESFWSKL--EVT-FNLRDAAG-G----L---H 722
KCNH7 840 DLLEVLDMYPEFSDHFLTNL--ELT-FNLRHESA-KA-DLLRSQS 879
KCNH8 646 GLFEVLDLYPEYAHKFVEDIQHDLT-YNLREGHE-SDVISR-L-- 685
HCN1 568 NFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSIL-LQKFQK---- 607
HCN2 637 NFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSIL-LHKVQH---- 676
HCN3 521 HFNAVLEEFPMMRRAFETVAMDRLLRIGKKNSIL-QRKRSE---- 560
HCN4 688 NFNEVLEEYPMMRRAFETVALDRLDRIGKKNSIL-LHKVQH---- 727
CNGA1 580 DLMEALTEYPDAKTMLEEKGKQILMKDGLLDLNI-ANAGSD-P-- 620
CNGA2 555 DLMEAVTEYPDAKKVLEERGREILMKEGLLDENE-VATS-M-E-- 594
CNGA3 583 DLMEALTEYPEAKKALEEKGRQILMKDNLIDEEL-ARAGAD-P-- 623
CNGA4 449 DLREVLSEYPQAQTIMEEKGREILLKMNKLDVNA-EAAEIA-L-- 489
CNGB1 1061 DLNEILVHYPESQKLLRKKARRMLRSNNKPK------EE-K-SVL 1097
CNGB3 623 TLQEILVHYPDSERILMKKARVLLKQKAKTA-EATPPRK-D-LAL 664
cons 1396 : : :. : : 1440
KCNH2 874 ----STELE-GGFSRQRKRKLSFRRRTDKDT--EQPGEVSALGPG 911
KCNH1 714 ----KREEE-ERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARL- 752
KCNH3 717 ------SLS-----G-------D--NTLMSTLEEKETDGEQG--- 738
KCNH4 701 ------SRS-PRLSQPRSESLGSSSDKTLPSITEAESGAEPGGGP 738
KCNH5 683 ----KKEEE-ERLRQKNEVTLSIPVDHPVRKLFQKFKQQKELRNQ 722
KCNH6 723 ----SSPRQ-APGSQDHQGFFLSDNQSGSPH--ELGPQFPSKGYS 760
KCNH7 880 ----MNDSE-GDNCKLRRRKLSFESEGEKE--------NSTNDPE 911
KCNH8 686 ------SNK-SMVSQSEPKGNGN-INKRLPSIVEDEEEEEEGEEE 722
HCN1 608 ------DLNTGVFNN-Q---ENEILKQIVKHDREMVQAIAPINYP 642
HCN2 677 ------DLNSGVFNN-Q---ENAIIQEIVKYDREMVQQAELGQRV 711
HCN3 561 ------PSPG----S-S---GGIMEQHLVQHDRDMARGVRGRAPS 591
HCN4 728 ------DLNSGVFNY-Q---ENEIIQQIVQHDREMAHCAHRVQAA 762
CNGA1 621 ----KDLEE-K---VTRME--GSVDLLQTRFARILAEYESMQQKL 655
CNGA2 595 ----VDVQE-K---LGQLE--TNMETLYTRFGRLLAEYTGAQQKL 629
CNGA3 624 ----KDLEE-K---VEQLG--SSLDTLQTRFARLLAEYNATQMKM 658
CNGA4 490 ----QEATE-SR--LRGLD--QQLDDLQTKFARLLAELESSALKI 525
CNGB1 1098 ILPPRAGTP-KL--FNAA--LAMTGKMGGKGAKGGKLAHLRARLK 1137
CNGB3 665 LFPPKEETP-KL--FKTL--LGGTGKASL------------ARLL 692
cons 1441 1485
KCNH2 912 RAGAGPSSRGRPGG---P--WGESPSSGPSS-------PESSEDE 944
KCNH1 753 AAERGGRDLDDLDV---E--KGNVLTEHASA-------NHSLVKA 785
KCNH3 739 P-TVSPAPADEPSS---P--LLSPGCTSSSSAAKLLSPRRTAPRP 777
KCNH4 739 RPR-RPLLLPNLSP---A--RPR--GSLVSLLGEELPPFSALVSS 775
KCNH5 723 GSTQGDPERNQLQV---E--SRSLQNGASIT-------GTSVVTV 755
KCNH6 761 LLGPG-SQNSMGAG---P--CAPG-HPDAAP-------PLSISDA 791
KCNH7 912 DSADTIRHYQSSKR---H--FEEKKSRSSSF-------ISSIDDE 944
KCNH8 723 EAVSLSPICTRGSS---S--RNKKVGSNKAYLGLSLKQLASGT-V 761
HCN1 643 QMTTLNSTSSTTTP---T--SRMRTQSPPVYT-------ATSLSH 675
HCN2 712 GLFPPPPPPPQVTS---A--IATLQQAAAMSF-------CPQVAR 744
HCN3 592 TGAQLSGKPVLWEP---L--VHAPLQAAAVTS-------NVAIAL 624
HCN4 763 ASATPTPTPVIWTP---L--IQAPLQAAAATT-------SVAIAL 795
CNGA1 656 KQRLTKVEKFLKP-----LIDTEFSSIEGPG---------AESGP 686
CNGA2 630 KQRITVLETKMKQ-----NNEDDYLSDGMNS---------PELAA 660
CNGA3 659 KQRLSQLESQVKG-----GG-DKPLADGEVPG-------DATKTE 690
CNGA4 526 AYRIERLEWQTREW---PMPEDLAEADDEGE---------PEEGT 558
CNGB1 1138 ELAALEAAAKQQEL---V--EQAKSSQDVKGE-------EGSAAP 1170
CNGB3 693 KLKREQAAQKKENSEGGE--EEGKENEDKQKE-------N-EDKQ 727
cons 1486 1530
KCNH2 945 GP---GRSSSPLRLVPFSSP-RPPGEPPGGEPLMEDC-------- 977
KCNH1 786 SV---VTVRESPATPVSFQA-ASTSGVPDHAKLQAPGS------- 819
KCNH3 778 RL---GGRGRPGRAGALKAE-AGPSAPPRALEG------------ 806
KCNH4 776 PS---LSPSLSPALAGQGHS-ASPHGPPRCSAAWKPPQ------- 809
KCNH5 756 SQ---ITPIQTSLAYVKTSE-SLKQNNRDAMELKPNGG------- 789
KCNH6 792 SG---LWPELLQEMPPRHSP-QSPQEDPDCWPLKLGSR------- 825
KCNH7 945 QK---PLFSGIVDSSPGIGK-ASGLDFEETVPTSGRMH------- 978
KCNH8 762 PF---HSPIRVSRSNSPKTK-QEIDPPNHNKRKEKNLK------- 795
HCN1 676 SNL-H--------------------------------------S- 680
HCN2 745 PLVGP---------------------------------------- 749
HCN3 625 THQRG--------P------------------------------- 630
HCN4 796 THHPRLPAAIFRPPPGSGLGNLGAGQTPRHLKRLQSLIPSALGSA 840
CNGA1 687 ID---S--------------------------------------- 689
CNGA2 661 AD---E--------------------------------------- 663
CNGA3 691 DK---Q--------------------------------------- 693
CNGA4 559 SK---DE-------E------------------------------ 563
CNGB1 1171 DQ----------HT-HPKEA------------------------- 1179
CNGB3 728 KE----------NEDKGKE-------------------------- 736
cons 1531 1575
KCNH2 978 --------------------------------------------- 977
KCNH1 820 --------------------------------------------- 819
KCNH3 807 --------------------------------------------- 806
KCNH4 810 --------------------------------------------- 809
KCNH5 790 --------------------------------------------- 789
KCNH6 826 --------------------------------------------- 825
KCNH7 979 --------------------------------------------- 978
KCNH8 796 --------------------------------------------- 795
HCN1 681 ----------------------------------PSPSTQTP--- 688
HCN2 750 ------------------------------------LALGSP--- 755
HCN3 631 ----------------------------------LPLSPDSP--- 638
HCN4 841 SPASSPSQVDTPSSSSFHIQQLAGFSAPAGLSPLLPSSSSSPPPG 885
CNGA1 690 --------------------------------------------- 689
CNGA2 664 --------------------------------------------- 663
CNGA3 694 --------------------------------------------- 693
CNGA4 564 --------------------------------------------- 563
CNGB1 1180 --------------------------------------------- 1179
CNGB3 737 --------------------------------------------- 736
cons 1576 1620
KCNH2 978 --------------------------------------------- 977
KCNH1 820 --------------------------------------------- 819
KCNH3 807 --------------------------------------------- 806
KCNH4 810 --------------------------------------------- 809
KCNH5 790 --------------------------------------------- 789
KCNH6 826 --------------------------------------------- 825
KCNH7 979 --------------------------------------------- 978
KCNH8 796 --------------------------------------------- 795
HCN1 689 --------------QPSAIL------------------------- 694
HCN2 756 ----------------RLVR------------------------- 759
HCN3 639 ---------------ATLLA------------------------- 643
HCN4 886 ACGSPSAPTPSAGVAATTIAGFGHFHKALGGSLSSSDSPLLTPLQ 930
CNGA1 690 --------------------------------------------- 689
CNGA2 664 --------------------------------------------- 663
CNGA3 694 --------------------------------------------- 693
CNGA4 564 --------------------------------------------- 563
CNGB1 1180 --------------------------------------------- 1179
CNGB3 737 --------------------------------------------- 736
cons 1621 1665
KCNH2 978 ---------------------EKSSDTCNPLSG-AFSGVSNIFS- 999
KCNH1 820 --------------------ECLGPKGGGGDCAKRKSWA----R- 839
KCNH3 807 --------------------LRLPPMPWNVPPDLSPRVVDGIED- 830
KCNH4 810 --------------------LLIPPLGTFGPPDLSPRIVDGIED- 833
KCNH5 790 --------------------ADQKCLKVNSPIRMKNGNGKGWLR- 813
KCNH6 826 --------------------LEQLQAQMNRLESRVSSDLSRILQ- 849
KCNH7 979 --------------------IDKRSHSCKDITDMRSWERENAHP- 1002
KCNH8 796 --------------------LQLSTLNNAGPPDLSPRIVDGIED- 819
HCN1 695 ----SPCSYTTAVCSPPVQSPLAARTFHYASPTASQLSLMQ---- 731
HCN2 760 ---RPPPGPAPAAASPG------------PPPPASP--------- 780
HCN3 644 ---RSAWRSAGSPASPL------------VPVRAGPWASTS---- 669
HCN4 931 PGARSPQAAQPSPAPPGARGGLGLPEHFLPPPPSSRSPSSSPGQL 975
CNGA1 690 --------------------------------------------- 689
CNGA2 664 --------------------------------------------- 663
CNGA3 694 --------------------------------------------- 693
CNGA4 564 --------------------------------------------- 563
CNGB1 1180 ---------------------------A------T---------- 1181
CNGB3 737 ---------------------------N------E---------- 738
cons 1666 1710
KCNH2 1000 ------------------------FWGDS---R----G------- 1006
KCNH1 840 ------------------------FKDAC---G------------ 845
KCNH3 831 ------------------------GCGSD---Q------------ 836
KCNH4 834 ------------------------SGSTA---E----A------- 840
KCNH5 814 ------------------------LKNNM---G----A------- 820
KCNH6 850 ------------------------LLQKP---M----P------- 856
KCNH7 1003 ------------------------QPEDS---S----P------- 1009
KCNH8 820 ------------------------GNSSE---E----S------- 826
HCN1 732 -----------------------QQPQ------------------ 735
HCN2 781 -------------------------PG------------------ 782
HCN3 670 -----------------------RLPA------------------ 673
HCN4 976 GQPPGELSLGLATGPLSTPETPPRQPEPPSLVAGASGGASPVGFT 1020
CNGA1 690 --------------------------------------------- 689
CNGA2 664 --------------------------------------------- 663
CNGA3 694 --------------------------------------------- 693
CNGA4 564 --------------------------------------------- 563
CNGB1 1182 -------------------------DPPA---------------- 1185
CNGB3 739 -------------------------DKDK---------------- 742
cons 1711 1755
KCNH2 1007 ----------------RQYQELPRCPAPTP-SLLNI--PL--SSP 1030
KCNH1 846 -------------------KSEDWNKVSKA-ESMET--LP--ER- 865
KCNH3 837 ----------------PKFSFRVGQSGPE--CSSSP--SP--GPE 859
KCNH4 841 ----------------PSFRFSRRPELPRP-RSQAP--PT--GTR 864
KCNH5 821 ----------------HEEKKEDWNNVTKA-ESMGL--LS--EDP 844
KCNH6 857 ----------------QGHASYILEAPASN-DLALV--PI--ASE 880
KCNH7 1010 ----------------SALQRAAWGISET---------------E 1023
KCNH8 827 ----------------QTFDFGSERIRSEP-RISPP--LG--DPE 850
HCN1 736 --QQ-------------VQQSQPPQTQPQQPS-PQPQTPGS---- 760
HCN2 783 --A-PA-------------SPRAPRTSPY---------------- 795
HCN3 674 --PP----------ARTLHASLSRAGRSQ-VSLLG--PP------ 697
HCN4 1021 PRGGLSPPGHSPGPPRTFPSAPPRASGSH-GSLLL--PPASSP-- 1060
CNGA1 690 ---------------------------T----------------- 690
CNGA2 664 ---------------------------P----------------- 664
CNGA3 694 ---------------------------Q----------------- 694
CNGA4 564 ----------------GRASQEGPPGPE----------------- 575
CNGB1 1186 ----------------PRTPPEPP---------G----SP--PSS 1199
CNGB3 743 ----------------GREPEEKPLDRPECTA-S----PI--AVE 764
cons 1756 1800
KCNH2 1031 GRRPRGDVE-SRLDALQRQLNRLETRLSADMATVLQ--------- 1065
KCNH1 866 -----TKAS------GEATLKKTDSCDSGITKSDLR--------- 890
KCNH3 860 SGLLTVPHG-PSEARNTDTLDKLRQAVTELSEQVLQ--------- 894
KCNH4 865 P-SPELASE-AEEVK--EKVCRLNQEISRLNQEVSQ--------- 896
KCNH5 845 KSSDSENSV------TKNPLRKTDSCDSGITKSDLR--------- 874
KCNH6 881 TTSPGPRLP-------QGFLPPAQTPSYGDLDDCSP--------- 909
KCNH7 1024 SDLTYGEVE-QRLDLLQEQLNRLESQMTTDIQTILQ--------- 1058
KCNH8 851 IGAAVLFIK-AEETK--QQINKLNSEVTTLTQEVSQ--------- 883
HCN1 761 STPKNEVHK-STQALHNTNLTREVRPLSASQPSLPHEVSTLISRP 804
HCN2 796 --GGLPAAPLAGPALPARRLSRASRPLSASQPSLPHGAPGPAAST 838
HCN3 698 ------------PGGGGRRLGPRGRPLSASQPSLPQRATGDGSPG 730
HCN4 1061 PPPQVPQRR-GTPPLTPGRLTQDLKLISASQPALPQDGAQTLRRA 1104
CNGA1 691 --------------------------------------------- 690
CNGA2 665 --------------------------------------------- 664
CNGA3 695 --------------------------------------------- 694
CNGA4 576 --------------------------------------------- 575
CNGB1 1200 PPPAS---------L------------------------------ 1205
CNGB3 765 EEPHS---------V------------------------------ 770
cons 1801 1845
KCNH2 1066 -----LLQRQMTLVPPAYSAVTTP--------------------- 1084
KCNH1 891 -----LDNVGEARSPQDRSPILAEVKHSF-------------YPI 917
KCNH3 895 -----MREGLQSLRQAVQLVLAPHREGP----------------- 917
KCNH4 897 -----LSRELRHIMGLLQARLGPP------------------GHP 918
KCNH5 875 -----LDKAGEARSPLEHSPIQADAKHPF-------------YPI 901
KCNH6 910 -----KHRNSSPRMP--HLAVATD--------------------- 926
KCNH7 1059 -----LLQKQTTVVPPAYSMVTAGSEYQR-------------PII 1085
KCNH8 884 -----LGKDMRNVIQLLENVLSPQQPSRFCSLHSTSVCPSRESLQ 923
HCN1 805 HPTVG----ESLASIPQPVTAVPGTGLQ----------------- 828
HCN2 839 RPAS----------------------------------------- 842
HCN3 731 RKGS----------------------------------------- 734
HCN4 1105 SPHSSGESMAAFPLFPRAGGGSGGSG------------------- 1130
CNGA1 691 --------------------------------------------- 690
CNGA2 665 --------------------------------------------- 664
CNGA3 695 --------------------------------------------- 694
CNGA4 576 --------------------------------------------- 575
CNGB1 1206 --------------------------------------------- 1205
CNGB3 771 --------------------------------------------- 770
cons 1846 1890
KCNH2 1085 ---GPGPTSTSPLL-----PVSPLP-TLTLDSLSQVSQFMACEEL 1120
KCNH1 918 PEQTLQATVLEVRH-----ELKEDIKALNAKMTNIEKQLSEILRI 957
KCNH3 918 -CPRASGEGPCPASTSGLLQPLCVDTGASSYCLQPPAGSVLSGTW 961
KCNH4 919 AGSAWTPDPPCPQL-----RP-----PCLSPCASRPPPSLQDTTL 953
KCNH5 902 PEQALQTTLQEVKH-----ELKEDIQLLSCRMTALEKQVAEILKI 941
KCNH6 927 ---KTLAPSSEQEQ-----PEGLWP-PLASPLHPLEVQGLICG-- 960
KCNH7 1086 QLMRTSQPEASIKT-----DRSFSPSSQCPEFLDLEKSKLKSKES 1125
KCNH8 924 TRTSWSAHQPCLHL-----QTGGAAYTQAQLCSSNITSDIWSVDP 963
HCN1 829 A-------GGRST--------------VP-QRVTLFRQMSSGAIP 851
HCN2 843 ---------SST-------------PRLG-P-------------- 850
HCN3 735 ---------GSE-------------R-LP-PSGLL-------AKP 748
HCN4 1131 --------SSGGLG-----PPGRPYGAIPGQHVTLPRKTSSGSLP 1162
CNGA1 691 --------------------------------------------- 690
CNGA2 665 --------------------------------------------- 664
CNGA3 695 --------------------------------------------- 694
CNGA4 576 --------------------------------------------- 575
CNGB1 1206 ---GRPEGEEEGPA-----EPEEHSVRIC---------------- 1226
CNGB3 771 ---RR----TVLPR-----GTSRQSLIIS---------------- 787
cons 1891 1935
KCNH2 1121 PPGAPELPQ------------------------------------ 1129
KCNH1 958 LTSRRS--------------------------------------- 963
KCNH3 962 PHPRPGPPPL--MAPWPWG-------PPASQSSP----------- 986
KCNH4 954 AEVH-CPASV--GTMETG--------TALLDLRP----------- 976
KCNH5 942 LSEKSVPQ------------------------------------- 949
KCNH6 961 --------------------------------------------- 960
KCNH7 1126 LSSGVHLNTA--SEDNLTSL------------------------- 1143
KCNH8 964 SSVGSSPQRT--GAHEQNPADSELYHSPSLDYSPSHYQVVQEGHL 1006
HCN1 852 ------PNRGVPPAPPPPA-------------------------- 864
HCN2 851 ---TP-AARAAAPSPDRRD-------------------------- 865
HCN3 749 ------PRTAQPPRPPVPE-------------------------- 761
HCN4 1163 PPLSLFGARATSSGGP-PL-------------------------- 1180
CNGA1 691 --------------------------------------------- 690
CNGA2 665 --------------------------------------------- 664
CNGA3 695 --------------------------------------------- 694
CNGA4 576 --------------------------------------------- 575
CNGB1 1227 --------------------------------------------- 1226
CNGB3 788 --------------------------------------------- 787
cons 1936 1980
KCNH2 1130 --------------------------------E--------G--P 1132
KCNH1 964 --------------------------------------------- 963
KCNH3 987 --WPRATAFWTSTSDSEPPASGDLCSEPSTPAS-------PP--P 1020
KCNH4 977 -----------SILPPYPSEPDPLG---------------PS--P 993
KCNH5 950 ---------------------------ASSPKS--------QMPL 959
KCNH6 961 --------------------------------------------P 961
KCNH7 1144 -------------LKQDSDLSLELHLRQRKTYV--------H--P 1165
KCNH8 1007 QFLRCISPHSDSTLTPLQSISATLSSSVCSSSETSLHLVLPS--R 1049
HCN1 865 --------------------------------------------- 864
HCN2 866 --------------------------------------------- 865
HCN3 762 --------------------------------------------- 761
HCN4 1181 --------------------------------------------- 1180
CNGA1 691 --------------------------------------------- 690
CNGA2 665 --------------------------------------------- 664
CNGA3 695 --------------------------------------------- 694
CNGA4 576 --------------------------------------------- 575
CNGB1 1227 --------------------------------------------- 1226
CNGB3 788 --------------------------------------------- 787
cons 1981 2025
KCNH2 1133 TRRLSLPGQLG---ALTSQP-LHRHGSDPG--------------- 1158
KCNH1 964 ------SQSPQ---ELFEISRPQSPESERDIFGA----------- 988
KCNH3 1021 SEEGAR-TGPA---EPVSQAEATSTGEPPPGSGGLALPWDPHSLE 1061
KCNH4 994 VPEASPPTPSL---LRHSFQSRSDTF------------------- 1016
KCNH5 960 QVP--PQIPCQ---DIFSVSRPESPESDKDEIH------------ 987
KCNH6 962 -CFSSLPEHLG---SVPKQLDFQRHGSDPGFAGSWG--------- 993
KCNH7 1166 IRHPSLPDSSL---STVGIVGLHRHVSDPGLPG------------ 1195
KCNH8 1050 SEEGSFSQGTV---SSFSLENLPGSWNQEGMASASTKPLENLPLE 1091
HCN1 865 ---AALPRESS---SVLNTD-P-DAEKP-RFASN----------- 889
HCN2 866 ---SASPGAAG---G---LD-PQDSARS-RLSSN----------- 888
HCN3 762 ---PATP------------------RGL-QLSAN----------- 773
HCN4 1181 ---TAGPQREP---G---AR-P-EPVRS-KLPSN----------- 1202
CNGA1 691 --------------------------------------------- 690
CNGA2 665 --------------------------------------------- 664
CNGA3 695 --------------------------------------------- 694
CNGA4 576 --------------------------------------------- 575
CNGB1 1227 ----MSPGPEPGEQILSVKMPEEREE-KAE--------------- 1251
CNGB3 788 ----MAPSAEGGEEVLTIEVKEKAKQ------------------- 809
cons 2026 2070
KCNH2 1159 ---------------------S 1159
KCNH1 989 ---------------------S 989
KCNH3 1062 MVLIGCHGSGTVQWTQEEGTGV 1083
KCNH4 1017 ---------------------H 1017
KCNH5 988 ---------------------F 988
KCNH6 994 ---------------------H 994
KCNH7 1196 ---------------------K 1196
KCNH8 1092 VVTS------TAEVKDNKAINV 1107
HCN1 890 ---------------------L 890
HCN2 889 ---------------------L 889
HCN3 774 ---------------------M 774
HCN4 1203 ---------------------L 1203
CNGA1 691 ---------------------- 690
CNGA2 665 ---------------------- 664
CNGA3 695 ---------------------- 694
CNGA4 576 ---------------------- 575
CNGB1 1252 ---------------------- 1251
CNGB3 810 ---------------------- 809
cons 2071 2092