Paralogue Annotation for KCNE1 residue 20

Residue details

Gene: KCNE1
Reference Sequences: LRG: LRG_290, Ensembl variant: ENST00000399289 / ENSP00000382228
Amino Acid Position: 20
Reference Amino Acid: T - Threonine
Protein Domain: N-terminus

Paralogue Variants mapped to KCNE1 residue 20

No paralogue variants have been mapped to residue 20 for KCNE1.

KCNE1	--MILS---NTTAVTPFLTKLWQE--->T<------VQQGGN-MSGLA-RRSPRSSDGKL	42
KCNE2	MSTLSN---FTQTLEDVFRRIFITYMD>N<W----RQNTTAEQEALQA-KVDAENFY--Y	48
KCNE3	METTNGTETWYESLHAVLKALNATLHS>N<LLCRPGPGLGPD-NQTEERRASLPGR-DDN	56
KCNE4	-------------------MLKMEPLN>S<T----HPGTAASSSPLES-RAAGGGSGNGN	34
cons	> <

See full Alignment of Paralogues

Known Variants in KCNE1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.T20I	c.59C>T	Inherited Arrhythmia	LQTS	rs199473349	SIFT: tolerated Polyphen: possibly damaging
Reports		Inherited Arrhythmia	LQTS	Contribution of long-QT syndrome genetic variants in sudden infant death syndrome. Pediatr Cardiol. 2009 30(4):502-9. 19322600