Paralogue Annotation for KCNE1 residue 60

Residue details

Gene: KCNE1
Reference Sequences: LRG: LRG_290, Ensembl variant: ENST00000399289 / ENSP00000382228
Amino Acid Position: 60
Reference Amino Acid: G - Glycine
Protein Domain: Transmembrane region

Paralogue Variants mapped to KCNE1 residue 60

No paralogue variants have been mapped to residue 60 for KCNE1.

KCNE1	A-RRSPRSSDGKLEALYVLMVLGFFGFFTL>G<IMLSYIRSKKLEHSNDPFNVYIESDA-WQE	89
KCNE2	A-KVDAENFY--YVILYLMVMIGMFSFIIV>A<ILVSTVKSKRREHSNDPYHQYIVED--WQE	94
KCNE3	ERRASLPGR-DDNSYMYILFVMFLFAVTVG>S<LILGYTRSRKVDKRSDPYHVYIKN------	98
KCNE4	S-RAAGGGSGNGNEYFYILVVMSFYGIFLI>G<IMLGYMKSKRREKKSSLLLLYKDEERLWGE	82
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See full Alignment of Paralogues

Known Variants in KCNE1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.G60D	c.179G>A	Inherited Arrhythmia	AF		SIFT: Polyphen:
Reports		Inherited Arrhythmia	AF	Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation. BMC Med Genet. 2012 13:24. 22471742