Paralogue Annotation for RYR2 residue 1025

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1025
Reference Amino Acid: K - Lysine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 1025

No paralogue variants have been mapped to residue 1025 for RYR2.

RYR2	MVDKLAENAHNVWARDRIRQGWTYGIQQDV>K<NRRNPRLVPYTLLDDRTKKSNKDSLREAVR	1055
RYR1	LVDRLAENGHNVWARDRVGQGWSYSAVQDI>P<ARRNPRLVPYRLLDEATKRSNRDSLCQAVR	1043
RYR3	LVDKLAENAHNVWAKDRIKQGWTYGIQQDL>K<NKRNPRLVPYALLDERTKKSNRDSLREAVR	1042
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.K1025R	c.3074A>G	Putative Benign			SIFT: Polyphen: