Paralogue Annotation for RYR2 residue 1432

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1432
Reference Amino Acid: I - Isoleucine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 1432

No paralogue variants have been mapped to residue 1432 for RYR2.

RYR2	ARLTEDVLADDRDDYDFLMQT-STYYYSVR>I<FPGQEPANVWVGWITSDFHQYDTGFDLDRV	1462
RYR1	PRLPHDVVPADNRDDPEIILNTTTYYYSVR>V<FAGQEPSCVWAGWVTPDYHQHDMSFDLSKV	1468
RYR3	PCLDSEAFQKRKQMQEILSHTTTQCYYAIR>I<FAGQDPSCVWVGWVTPDYHLYSEKFDLNKN	1364
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.I1432L	c.4294A>C	Putative Benign			SIFT: Polyphen: