Paralogue Annotation for RYR2 residue 1466

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1466
Reference Amino Acid: T - Threonine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 1466

No paralogue variants have been mapped to residue 1466 for RYR2.

RYR2	QEPANVWVGWITSDFHQYDTGFDLDRVRTV>T<VTLGDEKGKVHESIKRSNCYMVCAGESMSP	1496
RYR1	QEPSCVWAGWVTPDYHQHDMSFDLSKVRVV>T<VTMGDEQGNVHSSLKCSNCYMVWGGDFVSP	1502
RYR3	QDPSCVWVGWVTPDYHLYSEKFDLNKNCTV>T<VTLGDERGRVHESVKRSNCYMVWGGDIVAS	1398
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.T1466I	c.4397C>T	Putative Benign			SIFT: Polyphen: