Paralogue Annotation for RYR2 residue 1559

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1559
Reference Amino Acid: R - Arginine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 1559

No paralogue variants have been mapped to residue 1559 for RYR2.

RYR2	TYYQVEPSTKLFPAVFAQATSPNVFQFELG>R<IKNVMPLSAGLFKSEHKNPVPQCPPRLHVQ	1589
RYR1	TFFQVEPNTKLFPAVFVLPTHQNVIQFELG>K<QKNIMPLSAAMFQSERKNPAPQCPPRLEMQ	1597
RYR3	TCYQVEPNTKVFPAVFLQPTSTSLFQFELG>K<LKNAMPLSAAIFRSEEKNPVPQCPPRLDVQ	1493
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.R1559S	c.4677A>T	Putative Benign			SIFT: Polyphen: