Paralogue Annotation for RYR2 residue 1585

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1585
Reference Amino Acid: R - Arginine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 1585

No paralogue variants have been mapped to residue 1585 for RYR2.

RYR2	FELGRIKNVMPLSAGLFKSEHKNPVPQCPP>R<LHVQFLSHVLWSRMPNQFLKVDVSRISERQ	1615
RYR1	FELGKQKNIMPLSAAMFQSERKNPAPQCPP>R<LEMQMLMPVSWSRMPNHFLQVETRRAGERL	1623
RYR3	FELGKLKNAMPLSAAIFRSEEKNPVPQCPP>R<LDVQTIQPVLWSRMPNSFLKVETERVSERH	1519
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.R1585C	c.4753C>T	Putative Benign			SIFT: deleterious Polyphen: probably damaging