Paralogue Annotation for RYR2 residue 1590

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1590
Reference Amino Acid: F - Phenylalanine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 1590

No paralogue variants have been mapped to residue 1590 for RYR2.

RYR2	IKNVMPLSAGLFKSEHKNPVPQCPPRLHVQ>F<LSHVLWSRMPNQFLKVDVSRISERQGWLVQ	1620
RYR1	QKNIMPLSAAMFQSERKNPAPQCPPRLEMQ>M<LMPVSWSRMPNHFLQVETRRAGERLGWAVQ	1628
RYR3	LKNAMPLSAAIFRSEEKNPVPQCPPRLDVQ>T<IQPVLWSRMPNSFLKVETERVSERHGWVVQ	1524
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.F1590Y	c.4769T>A	Putative Benign			SIFT: Polyphen: