Paralogue Annotation for RYR2 residue 1726

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1726
Reference Amino Acid: I - Isoleucine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 1726

No paralogue variants have been mapped to residue 1726 for RYR2.



RYR2GLLRAGYYDLLIDIHLSSYATARLMMNNEY>I<VPMTEETKSITLFPD------ENKKHGLPG1750
RYR1GPLRAGYYDLLISIHLESACRSRRSMLSEY>I<VPLTPETRAITLFPPGRSTENGHPRHGLPG1764
RYR3GLLRSGFYDLLISIHLASAKERKLMMKNEY>I<IPITSTTRNIRLFPD------ESKRHGLPG1654
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.I1726Vc.5176A>G Putative BenignSIFT:
Polyphen: