Paralogue Annotation for RYR2 residue 1851

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1851
Reference Amino Acid: F - Phenylalanine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 1851

No paralogue variants have been mapped to residue 1851 for RYR2.

RYR2	LIKLFYTLLIMGIFHNEDLKHILQLIEPSV>F<KEAATPEEESDTL--E-K---ELS----VD	1871
RYR1	VLKLVSTLLVMGIFGDEDVKQILKMIEPEV>F<TEEEEEEDEEEEGEEEDEEEKEEDEEETAQ	1901
RYR3	VLKLIGTLLVMGVFDDDDVRQILLLIDPSV>F<GEHSAGTEEGAEK--E-E---VTQ----VE	1775
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.F1851L	c.5553T>A	Putative Benign		rs75230115	SIFT: tolerated Polyphen: probably damaging