Paralogue Annotation for RYR2 residue 1882

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1882
Reference Amino Acid: E - Glutamate
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 1882

No paralogue variants have been mapped to residue 1882 for RYR2.

RYR2	--E-K---ELS----VDDAK-LQGAGEE-->E<AKGGKRPKEGLLQMKLPEPVKLQMCLLLQY	1912
RYR1	EEEDEEEKEEDEEETAQEKEDEEKEEEEAA>E<GEKEEGLEEGLLQMKLPESVKLQMCHLLEY	1945
RYR3	--E-E---VTQ----VEEKA-VEAG----->E<KAGKEAPVKGLLQTRLPESVKLQMCELLSY	1813
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.E1882G	c.5645A>G	Putative Benign		rs376441643	SIFT: tolerated Polyphen: benign