Paralogue Annotation for RYR2 residue 2175

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 2175
Reference Amino Acid: M - Methionine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 2175

No paralogue variants have been mapped to residue 2175 for RYR2.



RYR2GLGDIMNNKVFYQHPNLMRALGMHETVMEV>M<VNVLGGGESKEITFPKMVANCCRFLCYFCR2205
RYR1SIGNIMNNKVFYQHPNLMRALGMHETVMEV>M<VNVLGGGESKEIRFPKMVTSCCRFLCYFCR2241
RYR3GLGDIMNNKVFYQHPNLMRVLGMHETVMEV>M<VNVLGT-EKSQIAFPKMVASCCRFLCYFCR2102
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Met2175Valc.6523A>G UnknownSIFT:
Polyphen: