Paralogue Annotation for RYR2 residue 26

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 26
Reference Amino Acid: A - Alanine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 26

No paralogue variants have been mapped to residue 26 for RYR2.

RYR2	MADGGE-GEDEIQFLRTDDEVVLQCT>A<TIHKEQQKLCLAAEGFGNRLCFLESTSNSK	56
RYR1	MGD-AE-GEDEVQFLRTDDEVVLQCS>A<TVLKEQLKLCLAAEGFGNRLCFLEPTSNAQ	55
RYR3	MAEGGEGGEDEIQFLRTEDEVVLQCI>A<TIHKEQRKFCLAAEGLGNRLCFLEPTSEAK	57
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.A26T	c.76G>A	Putative Benign		rs368974917	SIFT: tolerated Polyphen: possibly damaging