Paralogue Annotation for RYR2 residue 266

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 266
Reference Amino Acid: A - Alanine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 266

No paralogue variants have been mapped to residue 266 for RYR2.

RYR2	LLHGHMDECLTVPSGEHGEEQRRTVHYEGG>A<VSVHARSLWRLETLRVAWSGSHIRWGQPFR	296
RYR1	LFHGHMDECLTISPAD-SDDQRRLVYYEGG>A<VCTHARSLWRLEPLRISWSGSHLRWGQPLR	280
RYR3	LFHGH-DECLTIPSTDQNDSQHRRIFYEAG>G<AGTRARSLWRVEPLRISWSGSNIRWGQAFR	285
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.A266T	c.796G>A	Putative Benign		rs373326624	SIFT: tolerated Polyphen: benign
p.A266S	c.796G>T	Putative Benign			SIFT: Polyphen: