Paralogue Annotation for RYR2 residue 2861

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 2861
Reference Amino Acid: E - Glutamate
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 2861

No paralogue variants have been mapped to residue 2861 for RYR2.

RYR2	VTLSRDLHAMAEMMAENYHNIWAKKKKMEL>E<SKGGGNHPLLVPYDTLTAKEKAKDREKAQD	2891
RYR1	VTLSRELQAMAEQLAENYHNTWGRKKKQEL>E<AKGGGTHPLLVPYDTLTAKEKARDREKAQE	2925
RYR3	VVLSRELQGMVEVVAENYHNIWAKKKKLEL>E<SKGGGSHPLLVPYDTLTAKEKFKDREKAQD	2786
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.E2861G	c.8582A>G	Putative Benign			SIFT: tolerated Polyphen: possibly damaging