Paralogue Annotation for RYR2 residue 291

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 291
Reference Amino Acid: W - Tryptophan
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 291

No paralogue variants have been mapped to residue 291 for RYR2.

RYR2	HYEGGAVSVHARSLWRLETLRVAWSGSHIR>W<GQPFRLRHVTTGKYLSLMEDKNLLLMDKEK	321
RYR1	YYEGGAVCTHARSLWRLEPLRISWSGSHLR>W<GQPLRVRHVTTGQYLALTEDQGLVVVDASK	305
RYR3	FYEAGGAGTRARSLWRVEPLRISWSGSNIR>W<GQAFRLRHLTTGHYLALTEDQGLILQDRAK	310
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.W291G	c.871T>G	Putative Benign		rs80303323	SIFT: deleterious Polyphen: benign