Paralogue Annotation for RYR2 residue 3225

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 3225
Reference Amino Acid: G - Glycine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 3225

No paralogue variants have been mapped to residue 3225 for RYR2.

RYR2	LSLPTNVEDVCPNIPSLEKLMEEIVELAES>G<IRYTQMPHVMEVILPMLCSYMSRWWEHGPE	3255
RYR1	LGLPNSVEEMCPDIPVLERLMADIGGLAES>G<ARYTEMPHVIEITLPMLCSYLPRWWERGPE	3290
RYR3	LGMPDTVEDMCPDIPQLEGLMKEINDLAES>G<ARYTEMPHVIEVILPMLCNYLSYWWERGPE	3151
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.G3225S	c.9673G>A	Putative Benign			SIFT: deleterious Polyphen: possibly damaging