Paralogue Annotation for RYR2 residue 3420

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 3420
Reference Amino Acid: V - Valine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 3420

No paralogue variants have been mapped to residue 3420 for RYR2.



RYR2PEAEELFRMVAEVFIYWSKSHNFKREEQNF>V<VQNEINNMSFLITDTKSKMSKAA-----VS3445
RYR1PSAEELFRMVGEIFIYWSKSHNFKREEQNF>V<VQNEINNMSFLTADNKSKMAKAGDIQSGGS3489
RYR3ADSDQLFRMVAEVFILWCKSHNFKREEQNF>V<IQNEINNLAFLTGDSKSKMSKAMQVKSGGQ3346
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.V3420Ic.10258G>A Putative BenignSIFT:
Polyphen: