Paralogue Annotation for RYR2 residue 3458

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 3458
Reference Amino Acid: R - Arginine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 3458

No paralogue variants have been mapped to residue 3458 for RYR2.



RYR2TDTKSKMSKAA-----VSDQERKKMKRKGD>R<YSMQTSLIVAALKRLLPIGLNICAPGDQEL3488
RYR1ADNKSKMAKAGDIQSGGSDQERTKKKRRGD>R<YSVQTSLIVATLKKMLPIGLNMCAPTDQDL3532
RYR3GDSKSKMSKAMQVKSGGQDQERKKTKRRGD>L<YSIQTSLIVAALKKMLPIGLNMCTPGDQEL3389
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R3458Qc.10373G>A Putative BenignSIFT:
Polyphen: