Paralogue Annotation for RYR2 residue 3491

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 3491
Reference Amino Acid: L - Leucine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 3491

No paralogue variants have been mapped to residue 3491 for RYR2.

RYR2	MQTSLIVAALKRLLPIGLNICAPGDQELIA>L<AKNRFSLKDTEDEVRDIIRSNIHLQGKLE-	3520
RYR1	VQTSLIVATLKKMLPIGLNMCAPTDQDLIT>L<AKTRYALKDTDEEVREFLHNNLHLQGKVEG	3565
RYR3	IQTSLIVAALKKMLPIGLNMCTPGDQELIS>L<AKSRYSHRDTDEEVREHLRNNLHLQEKSD-	3421
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.L3491V	c.10471C>G	Putative Benign			SIFT: Polyphen: